First trimester High maternal haemoglobin -- an independent risk factor for Pre-eclampsia (PIH)
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 7
Abstract
To know the association of first trimester, high maternal haemoglobin with occurrence of pre-eclampsia (PIH). Pre-eclampsia is a pregnancy specific, multisystem, hypertensive disorder characterized by new onset hypertension and proteinuria after 20 weeks of gestation and remission of signs after delivery, which is the leading cause of maternal, fetal and neonatal mortality and morbidity . Despite extensive research, the etiology and pathogenesis of Pre-eclampsia remain obscure and poorly understood. So are the association of first trimester, high maternal haemoglobin with occurrence of pre-eclampsia (PIH). The longitudinal study was conducted in the 200 pregnant women, who were enrolled in first trimester of pregnancy and followed till the delivery, with 100 pregnant women with haemoglobin >13gm% as cases and100 pregnant women haemoglobin 11 to 13 gm% as controls. Statistical analysis was done by using Chi-square test. The pregnant women with higher haemoglobin concentration in first trimester had higher risk of developing pre-eclampsia (PIH) comparing to other pregnant women. (p value –0.003). With higher haemoglobin concentration in first trimester of pregnancy, there is higher risk for developing pre-eclampsia. Keywords: First trimester, Haemoglobin, Pre-eclampsia
Authors and Affiliations
Dr Manjunatha S, Dr Amruta S Bennal, Dr. R H Taklikar
Keywords
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