FIXED DRUG ERUPTION
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 7
Abstract
Fixed drug eruption is a drug induced skin eruption characterized by one or multiple skin erythematous plaques that disappears once the culprit drug is withdrawn leaving hyper pigmented sequelae. These plaques are termed fixed because they reappear on the same location each time the drug is administered. The commonly implicated drugs are tetracyclines, paracetamol and sulfonamides. A 38 yrs. old male patient presented to the department of medicine with history of erythematous patches all over the body. Patient was administered tablet Augmentin 625 mg for upper respiratory tract infection 4 days back. After taking the tablet he noticed a small erythematous patch on the right shoulder which increased in size and some patches are spread all over the body i.e. on back, proximal part of limbs and on abdomen. The patches were distinct sizes with hyperpigmentation and necrosis in the center. In the present case fixed drug eruption would be related to amoxicillin that is present in Augmentin in a view of a suggestive temporal relationship between drug intake and reaction onset, the remission of skin eruption after withdrawal. Hence caution is needed in patients who are hypersensitivity to amoxicillin.
Authors and Affiliations
Balakrishna Balakrishna, Souri S. Kondaveti, Bhuvaneshwari Bhuvaneshwari
Keywords
Related Articles
- EP ID EP224234
- DOI 10.18410/jebmh/2015/134
- Views 57
- Downloads 0
THE STUDY OF NUTRIENT FORAMINA IN HUMAN CLAVICLE
BACKGROUND The major blood supply to the long bones is through nutrient arteries, which enter the medullary cavity of bone through the nutrient foramina. Nutrient foramen is the opening present in the shaft of long bone....
CLINICAL PROFILE, AETIOLOGY & EEG CHARACTERISTICS OF NEONATAL SEIZURES
BACKGROUND Seizures are a common neonatal neurologic emergency, affecting approximately 1-4 per 1000 live births. The first 28 days of life (defining the neonatal period) represents the period of greatest seizure hazard...
MORPHO-HISTOLOGICAL STUDY OF MYOCARDIAL BRIDGES OF CADAVERIC HEARTS
INTRODUCTION: A band overlying the intramural segment of coronary artery-a place where the artery goes through myocardium instead of epicardium is called myocardial bridging (MB). A wide variation of 0.5%-90.4% occurs in...
INTRAUTERINE FETAL DEATH CASES AT TERTIARY CENTER
BACKGROUND Intrauterine fetal death is a tragic event for the parents and a great cause of stress for the caregiver. It is an important indicator of maternal and perinatal health of a given population. This study was und...
ROLE OF INTRANASAL STEROIDAL SPRAY IN SEASONAL ALLERGIC RHINITIS WITH OCULAR SYMPTOMS
BACKGROUND The eye is especially susceptible to the symptoms of allergic rhinitis, itching (pruritus), tearing (epiphora) and redness (erythema) because it lacks a mechanical barrier that could prevent the deposition of...