Follow Up and Treatment of Women With Epilepsy During Pregnancy
Journal Title: Journal of Neurological Sciences-Turkish - Year 2012, Vol 29, Issue 3
Abstract
Objectives: More than 90 percent of pregnant women who have epilepsy deliver healthy babies. However, antiepileptic drugs (AED) that were used, genetic and socio-economic causes of maternal seizures can adversely affect the health of the fetus. Here, epileptic pregnant women, who were followed up in our epilepsy outpatient department, were discussed. Methods: This study was included eighty-seven pregnancies from 83 epileptic women who were following in our epilepsy department and had a child between June 2002-January 2012. All demographic data, medical and epileptic history, data about pregnancy, antiepileptic drugs malformations for each patient were evaluated. Results: The mean age of patients was 26.99 ± 4.73 and epilepsy duration was 8.49±6.23 years. There was focal onset seizure (with or without secondary generalisation) in fifty-two patients (62.7%). The remaining thirty-one patients had generalized seizures. Fifty-one pregnancies were planned. Before pregnancy, AED or drug dosage was changed in 36 women, pregnancy was allowed after the discontinuation of AED in two patients. Six pregnancies were ended with spontaneous abortus in the first trimaster and ectopic pregnancy was present in one patient, while seventy-six infants were healthy. Four patients had a major malformation (two gastrochisis, one ventriculoseptal defect, one meningocele). Five patients in spontaneous abortus and three patients who had major malformation infant were unplanned pregnancies. Conclusion: Pregnancy in women with epilepsy must be planned and the regulation of treatment should be done before pregnancy.
Authors and Affiliations
Gulnihal Kutlu, Abidin Erdal, Selma Aydogan, Yasemin Gomceli, Levent Inan
Keywords
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