Formulation and evaluation of chitosan nanoparticles containing Zidovudine for the target delivery into the brain
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 2
Abstract
Chitosan nanoparticles of Zidovudine (AZT), coated with Polysorbate 80 were prepared in the present study. The technique used in the preparation of nanoparticles was spontaneous emulsification. The nanoparticles were prepared by varying polymer and drug ratios. Characterization of nanoparticles and in-vitro evaluation of drug release was studied. This work presents a complete experimental approach to the preparation of Chitosan nanoparticles containing Zidovudine for the target delivery into the brain.
Authors and Affiliations
B. Raja, K. Narendra Kumar Reddy, P. Swetha
Keywords
Related Articles
- EP ID EP33446
- DOI -
- Views 312
- Downloads 0
An Introduction to Malt Production and Malt Mixing
Production of malt is a complicated technological method including soaking, sprouting and drying of sprouted malt in controlled conditions of temperature and moisture. Constant development in developing countries like I...
Formulation and evaluation of Telmisartan orodispersible tablets by using banana powder
The aim of this research is to introduce and evaluate natural excipient (banana powder) that has versatile property in the orally disintegrating tablets using Telmisartan as model drug. Oral disintegrating tablets are...
Preliminary phytochemical evaluation of Azadirachta indica, Justicia adhatoda, Cassia fistula
In the present study, an attempt was made to investigate phytochemical evaluation of Azadirachta indica, Justicia adhatoda, Cassia fistula. The crude power extract of the leaves of the above plant were taken for the st...
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF OLMESARTAN MEDOXOMIL BY RP-UPLC IN BULK AND PHARMACEUTICAL DOSAGE FORMS
A simple rapid, accurate, precise and reproducible validated reverse phase UPLC method was developed for the determination of Olmesartan medoxomil in bulk and pharmaceutical dosage forms. The quantification was carried...
Highly selective, sensitive and precise Bioanalytical method for the estimation of amoxicillin and clavulanic acid in nano gram range in Albino rat's plasma
LC-MS/MS method for the determination of amoxicillin and clavulanic acid in Albino rat's plasma was developed and validated according to currently accepted FDA guidelines of Bioanalytical method validation. The retenti...