Formulation peel-off gel mask of Impatiens balsamina l. as an antibactery against Staphylococcus aureus
Journal Title: Jurnal Kedokteran dan Kesehatan Indonesia - Year 2018, Vol 9, Issue 3
Abstract
Background: Acne is a skin disorder characterised by inflammation, accompanied by a blockage of the oil glands in the skin. One of the causes of acne is Staphylococcus aureus bacteria. Many plants have been widely studied as an antibacterial agent, including Garden Balsam Leaf (Impatiens balsamina L.) which could be formulated in a peel-off gel preparation. Objective : The purpose of this research was formulating an antibacterial peel-off gel mask with a variation of viscosity enhancing agent hydroxypropyl methylcellulose (HPMC), as well as testing its antibacterial activity on Staphylococcus aureus. Methods : HPMC 1-2% was formulated in peel-off gel mask of Garden Balsam leaf extract. Physical properties such as viscosity, pH, spreadability, and drying time were tested, while antibacterial activity test was conducted by the agar-diffusion method. Results : The viscosity of the entire formula was > 20,000 cP, pH 6, drying time > 20 minutes, and spreading power > 6 cm. Also, the peel-off gel mask also showed antibacterial activity on Staphylococcus aureus with average inhibition zone were > 10 mm, which indicated strong antibacterial inhibitory power. Conclussion : The concentration variation of HPMC had a significant effect on all physical properties test. HPMC 1.5% in the preparation showed the most optimum results.
Authors and Affiliations
Fitriani Mahyun, Aris Perdana Kusuma, Hady Anshory
Keywords
Related Articles
- EP ID EP443148
- DOI 10.20885/jkki.vol9.iss3.art6
- Views 119
- Downloads 0
Spiritual medicine in the multi perspective of religion
Spiritual healing, also known as healing through prayer and meditation, has been widely studied by various scholars from different religions including Islam, Hindu, Buddhism and Christianity. The term spiritual medicine...
The effect of tumeric rhizome (Curcuma longa L) on radial arm maze and passive avoidance test in trimethyltin-induced rat models
Backround: Oxidative stress can cause death of hippocampal cells associated to the deficit of learning and memory function. Turmeric rhizome contains curcuminoid which has antioxidant activity that can prevent oxidative...
Risk factors sharp injury among healthcare workers in Sleman State Hospital Yogyakarta province Indonesia
Background: The sharp injury is the most burden problem among healthcare workers. The prevalence slightly increased as consequences spreading blood-borne pathogen. Some researchers had found several variables associated...
The emotion regulation training to improve quality of life in patients with hypertension
Background : Quality of life is an indicator of health. Quality of life is used to evaluate the physical and psychosocial effects of an illness suffered by a person, including a person’s knowledge and perception of the i...
Blood, Bone and Brain Nocardiosis Infection in an HIV-Infected Man
Disseminated nocardiosis is a rare and complicated opportunistic bacterial infection with propensity of delay in establishing the correct diagnosis and high frequency for misdiagnosis and due to the non-specific clinical...