Frequency, preferences and prescribing pattern of antihypertensive drugs in Out-Patient Department of a tertiary care SGM Hospital, Rewa district of Madhya Pradesh, India
Journal Title: The Indian Practitioner - Year 2016, Vol 69, Issue 78
Abstract
Aims and Objectives: The aim of study was to determine the frequency and prescribing pattern of antihypertensive drugs in Out Patient Department of a tertiary care hospital and to identify whether the pattern of prescribing is appropriate in accordance with national and international guidelines for pharmacotherapy of hypertension. Methods: This was a prescription-based survey; the prescriptions were collected randomly from OPDs of SGM Hospital as xerox copies after taking the consent of the patients. A total of 3587 prescriptions were analysed. Results: In the 3587 prescriptions a total 8144 drugs were prescribed; of these only 4.19% (342) drugs belonged to the cardiovascular group. Among the cardiovascular drugs 94.73% (324) belonged to antihypertensive and 5.26% were anti-CHF drugs. 91.35% drugs were prescribed as monotherapy and 8.64% as combination therapy. The Calcium channel blockers (CCBs) (Amlodipine 83.47%) were the most frequently prescribed antihypertensive drugs (35.49%) followed by Angiotensin-converting-enzyme inhibitors (ACEIs) 25% (Enalapril 60.49%), β-blockers 13.27% (Atenolol 69.76%), angiotensin (AT1) receptor antagonists or angiotensin receptor blockers (ARBs) 9.25% (Losartan 80.0%), combination therapy 8.64% (AT+AM / LO+HCTZ 46.42%) and diuretics 8.33% (Hydrochlorothiazide 55.55%). However over all prescribing frequency among antihypertensive drugs were as follows: Amlodipine (29.63%) ≥ Enalapril (15.12%) ≥ Ramipril (9.87%) ≥ Atenolol ≥ (9.25%) ≥ Losartan (7.40%) hydrochlorothiazide ≥ (4.63%) ≥ Es-amlodipine (4.32%) ≥ AT+AM (4.01%)= LO+HCTZ (4.01%) ≥ Frusemide (3.70%) ≥ Candesartan (1.85%) ≥ Metoprolol (1.54%) and others. Conclusions: Most of antihypertensive drugs in this study were prescribed as monotherapy. Amlodipine was most frequently prescribed antihypertensive followed by Enalapril ≥ Ramipril ≥ Atenolol ≥ and Losartan, in combination therapy AT+AM and LO+HCTZ were equally prescribed. The pattern of this study was in accordance with the National and International guidelines.
Authors and Affiliations
Prabhakar Singh, Keshav Singh, Roshani Shrivastava, Vivek Pandey, Amita Singh, Raj Bhupendra
Keywords
Related Articles
- EP ID EP563321
- DOI -
- Views 48
- Downloads 0
A new ray of hope for uncomplicated falciparum malaria in India - A critical review
According to WHO report 2011, 4.3 million malaria cases were reported in the year 2010, of which 2.4 million were parasitologically confirmed. Three countries accounted for 94% of the confirmed cases: India (66%), Myanma...
A case of Vasmol Poisoning: Monitoring and treatment
We report a case of suicidal ingestion of hair dye that presented with cervicofascialoedema and later developed rhabdomyolysis and liver cell injury. Our patient improved with symptomatic management
To study the incidence and prevalence of Iron Deficiency Anaemia in adult males - A prospective study
Objectives: To find the incidence and prevalence of iron deficiency anaemia (IDA) among adult males followed up in a tertiary teaching hospital of Mumbai. To study aetiological factors and clinical profile of iron defici...
Evaluation of gastric lavage in the diagnosis of childhood pulmonary tuberculosis using gabbet’s cold stain
Introduction: Childhood tuberculosis is an important public health problem especially in developing countries like India. The diagnosis of tuberculosis is extremely challenging. The reason for this is the inability to de...
A Study of The Clinical Profile and Pattern of Acute Febrile Illness in a Teaching Hospital in Central Mumbai
AIMS AND OBJECTIVES : Fever remains the commonest cause of OPD and indoor admissions, in underdeveloped and developing countries including India. The present study was undertaken to study the fever profile, compare the a...