Fungal Infection in Paediatric Cancer Patients of a Tertiary Care Hospital in North India
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 2
Abstract
Introduction- Paediatric cancer patients undergoing chemotherapy are at high risk of developing fungal infection which remains a major cause of morbidity and mortality. But the burden of fungal infection in most of our population is still not well known. Our study was aimed to estimate burden and outcome of fungal infection in paediatric cancer patients. Objectives -To identify different fungal isolates and their antifungal susceptibility pattern in these patients. Methodology- This study was a hospital based observational study conducted in Department of Microbiology and Paediatric cancer unit, King George’s Medical University, Lucknow, UP for a period of one year. In this study we analysed 209 symptomatic paediatric cancer patients. Result- Out of 209 patients 78 fungal isolates were isolated from different clinical samples. Candida species were the leading pathogen (62/78) followed by Aspergillus species (16/78). A total of 19 patients of invasive fungal infection were diagnosed from positive blood culture. Only one patient was having both candidemia and candiduria from enrolled patients. Conclusion- Though incidence of fungal infection is lower than bacterial infection but mortality rate remains high due to fungal infection. So it is necessary to introduce efficient methods of prevention, diagnosis and treatment of fungal infections in paediatric cancer patients.
Authors and Affiliations
Anju Dinkar
Keywords
Related Articles
- EP ID EP210927
- DOI -
- Views 61
- Downloads 0
Prevalence and Microbial Etiology of Surgical Site Infections Following Major Abdominal Gynecologic Surgeries in a Tertiary Care Center
Background and Objective- Surgical site infections (SSI) are one of the common healthcare associated infections and account for approximately a quarter of all nosocomial infections.. The risk factors and microbial etiolo...
To study knowledge, attitude and actual practices regarding Mahatma Jyotiba Phule Jan Arogya Yojana at tertiary care hospital of MaharashtraA cross sectional study
MJPJAY is a state sponsored publically funded health insurance scheme (PFHI) launched by Govt. of Maharashtra. It provides free quality critical care for low income families. At tertiary care hospital, specialist is the...
Preeclampsia Risk and AGT M235T Gene in North India
Background: Pregnancy induced hypertension is considered to be a multifactorial and multisystemic disorder with a genetic predisposition. Aim: The aim of this original research article is to investigate the frequency of...
Seizure Pattern and Biochemical Abnormality in Neonatal Seizure
Abstract
Gender, Trunk Muscle Endurance and Static Balance in Young Adults
Balance and muscular endurance gender-related differences are very controversial. Objective: This study aimed at examining the difference between young adult males and females in trunk muscles’ endurance and static balan...