Fungating sister mary joseph’s nodule as an initial manifestation of transverse colon adenocarcinoma
Journal Title: Scientific Journal of Medical Science - Year 2013, Vol 2, Issue 6
Abstract
Sister Mary Joseph’s nodule refers to a palpable umbilical metastasis secondary to underlying abdominopelvic malignancies (gastric, colonic, pancreatic, ovarian and uterine cancer). The clinical appearance varies from small nodule to a large fungating or ulcerated lesion. Proposed hypothesis for spread is through direct trans-peritoneal extension via lymphatic running along the obliterated umbilical vein, hematogenous spread or via median umbilical ligament or a remnant of the umbilical duct. Sister Mary Joseph nodule is associated with dismal prognosis. Here-in we present a case of 76 year old Saudi woman who presented with initial manifestation of Sister Marry Joseph’s nodule which subsequently diagnosed as case of underlying metastatic adenocarcinoma of transverse colon and was treated with systemic chemotherapy and radiotherapy to Sister Marry Joseph’s nodule.
Authors and Affiliations
M. A. Tunio*| Assistant Consultant, Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh-59046, Saudi Arabia., R. Akasha| Resident, Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh-59046, Saudi Arabia., M. AlAsiri| Consultant, Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh-59046, Saudi Arabia., K. Riaz| Resident, Radiation Oncology, Comprehensive Cancer Center, King Fahad Medical City, Riyadh-59046, Saudi Arabia.
Keywords
Related Articles
- EP ID EP1236
- DOI -
- Views 420
- Downloads 24
Cardio-protective and cholesterol lowering effects of garlic (Allium sativum) and ginger (Zingiber officiale) extracts in laboratory animals
Garlic and ginger have attracted particular attention ofmodern medicine because of their wide spread use around the world and thecherished belief that they help to maintain good health by warding off illnessand providing...
Genetic pheochromocytoma/paraganglioma– A review
The prevalence of pheochromcytoma in hypertensive patients is less than 1%.Most PHEOs occur sporadically, but a substantial proportionmay be associated with germ line mutations of genes predisposing to thedevelopment o...
Is it worth to give steroid in caudal epidural injections? A prospective randomized controlled study
Background: Epidural injection, besides surgical decompression, is now one of the most common modality of treatment in lumbar disc herniation who doesn’t responds to conservative therapy. The main aim of our study was to...
Antenatal detection of congenital cytomegalovirus infection (a comparative study between serological and molecular identification of cytomegalovirus infection)
Cytomegalovirus, or CMV, is a common virus that infects most people worldwide. CMV infection is usually harmless and rarely causes illness. A healthy immune system can hold the virus in check. However, if a person's immu...
Effects of intramuscular injection of artemether® on the histology of the uterus and ovaries of pregnant wistar rats
This experiment was aimed at studying some of the histological effects of Artemether® on the uterus and ovaries of pregnant Wister Rats. Twelve pregnant rats were divided equally into treated and control groups. The rats...