Gall bladder carcinoma (GBC): Rising incidences in the Malwa belt region of northern India a hospital based cancer registry
Journal Title: Medpulse International Journal of Medicine - Year 2018, Vol 6, Issue 3
Abstract
A prospective study conducted in the department of Radiation Oncology at Guru Gobind Singh Medical College and Hospital, Faridkot, including all the gall bladder cancers (GBC) presenting over a 48 months period and analysing how the epidemiological factors were influencing the disease. This data was collected from all over the Malwa region which comprises mainly of three regions, Malwa, Majha and Doaba. The total number of GBC cases registered in this area were 244 over this period. The rural versus urban distribution was 68.6% to 31.5%. Incidence reported were about Four cases per 100,000 populations per year. The peak incidence was observed in the 51 to 60 years age group (32.3%) patients. Female to male ratio was 3.36, as opposed to the male preponderance in other regions. The most common clinical presentation were pain abdomen and loss of appetite. Amongst the various risk factors, fatty diet along with spices in 175-180 (80-83%) patients and gall stones in 154 (71%) patients were found as the most common culprits. Out of all the cases, 29 (11.88%) patients were overweight with BMI between 25 and 29.9 (p = 0.003), as against the majority who presented as undernourished which correlated with advanced stages. Adenocarcinoma was the most common histopathology seen in 181(75.5%) patients. Subtle onset of symptoms explains the advanced stage at initial resentation. Almost 49.1% patients presented with T3 and 38.7% with T4 stage at the time of initial presentation. This data highlights high prevalence of gall bladder carcinoma in North-western belt of India. Better hygiene and water supply, prevention of malnutrition, early intervention for cholelithiasis, importance of balanced diet, increase in awareness about risk of tobacco and alcohol consumption all are highlighted as significant modifiable factors.
Authors and Affiliations
Sapna Marcus, Jasmeet Kaur, H P Yadav
Keywords
Related Articles
- EP ID EP361206
- DOI -
- Views 75
- Downloads 0
A study on the prevalence of dilated cardiomyopathy in chronic alcoholics
Background: Dilated cardiomyopathy (DCM) is an important cause of congestive heart failure and accounts for up to 25% of all cases of CHF. The incidence of DCM appears to be increasing and is associated with significant...
A study of prevalence of metabolic syndrome in newly detected diabetes mellitus type 2
Background: The metabolic syndrome (MS) is described as insulin resistance, hypertension, hyperglycaemia, increased triglycerides, and decreased high cholesterol (HDL-C). Material and Method: Mellitus (< 6 months duratio...
A Study of various complications among type II diabetic patients at rural tertiary heath care center
Background: The present situation about diabetes the prevalence of these complications and possible risk factors in order to develop potential preventive programmes. Aims and Objectives: To Study center. Methodology: Aft...
Grading and frequency of pulmonary hypertension in chronic obstructive pulmonary disease patients
Background: India is a developing country, and due to industrialization, the incidence of COPD has been increasing day by day. Pulmonary hypertension (PH) is most common complication of Chronic Obstructive Pulmonary Dise...
Comparative study of complications associated with femoral and radial approach for coronary angiography
Background: The knowledge about different diameter of the head and neck of the femur is essential in orthopedic surgery and for radiological practice in identifying pathology of bone. The femoral normative values are als...