GASTRORETENTIVE DOSAGE FORMS: REVIEW ON FLOATING DRUG DELIVERY SYSTEMS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 5
Abstract
Gastroretentive drug delivery system has been a significant approach over the past few years that have been noted to prolong gastric residence time, thereby targeting site-specific drug release in the upper gastrointestinal (GI) tract for local or systemic effects. The present study has been investigated to compile the recent as well as past literature with special focus on various gastroretentive approaches that have recently become leading methodologies in the field of site-specific orally administered controlled release drug delivery. Floating systems have been considered as one of the imperative categories of drug delivery systems with gastric retentive behavior. The review article explains the various floating drug delivery systems that are formulated in order to enhance the drug bioavailability. Moreover, various gastroretentive approaches designed and developed such as high density, floating, bioadhesive, super porous hydrogel and magnetic systems have been clearly discussed in the article.
Authors and Affiliations
Amarjeet Dahiya , Ankur Rohilla , Seema Rohilla , M. U. Khan
Keywords
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