GC-MS ANALYSIS OF FIXED OILS OF NIGELLA SATIVA SEEDS

Journal Title: Universal Journal of Pharmaceutical Research - Year 2018, Vol 3, Issue 2

Abstract

Gas chromatography-Mass spectrometry (GC-MS) is an analytical method that combines the features of gas-liquid chromatography and mass spectrometry to identify different substances within a test sample. Applications of GC-MS include drug detection, fire investigation, environmental analysis, explosives investigation, and identification of unknown samples. The present study also relies on use of GC-MS for detection and interpretation of compounds present in N. sativa oil samples. Fixed oil was obtained through column chromatography of ethyl acetate fraction. The oil samples were subjected to GC-MS analysis which showed 5, 18, 12 and 20 compounds in four fixed oil samples respectively. The major components were linoleic acid, methyl ester (35.5%), oleic acid, methyl ester (15.007%), palmitic acid, methyl ester (8.208%).

Authors and Affiliations

Sania Feroz, Ghias Uddin

Keywords

Related Articles

FORMULATION AND EVALUATION OF ETODOLAC NIOSOMES BY MODIFIED ETHER INJECTION TECHNIQUE

Etodolac is an indole acetic acid derivative with half-life of 4 to 7 hrs. It is used for the treatment of Rheumatoid arthritis. Whenever used orally, it has many systemic side effects, so it is not preferred orally. In...

A REVIEW OF BREAST CANCER RISK FACTORS

Breast cancer is a commonly diagnosed neoplastic ailment in females particularly near menopause. This ailment signifies a substantial health problem as it has influenced a large number of women. Several risk factors are...

INTERLEUKIN-22 SERUM LEVELS IN PATIENTS WITH RHEUMATOID ARTHRITIS IN SANA'A CITY, YEMEN

Interleukin (IL) -22 is a novel mediator of a member of IL-10 family cytokines that is produced by many different types of lymphocytes including both those of innate and adaptive immune system. This cytokine has potent p...

AWARENESS AMONGST YOUTH ABOUT USE AND ABUSE OF STEROIDS IN KARACHI, PAKISTAN

Aim of present study was to analyze awareness regarding the use of steroids in the youth studying health sciences. A descriptive, observational study was conducted from September to December 2017. Youth studying health...

FORMULATION AND EVALUATION OF FINASTERIDE SUSTAINED-RELEASE MATRIX TABLETS USING DIFFERENT RATE CONTROLLING POLYMERS

The aim of the present investigation was to develop oral controlled release matrix tablet formulations of Finasteride with different polymer ratios. Finasteride is chemically considered a synthetic 4-azasteroid drug. The...

Download PDF file
  • EP ID EP36457
  • DOI https://doi.org/10.22270/ujpr.v3i2.139
  • Views 352
  • Downloads 0

How To Cite

Sania Feroz, Ghias Uddin (2018). GC-MS ANALYSIS OF FIXED OILS OF NIGELLA SATIVA SEEDS. Universal Journal of Pharmaceutical Research, 3(2), -. https://europub.co.uk./articles/-A-36457