GC-MS ANALYSIS OF THE METHYLENE CHLORIDE AND n-BUTANOL FRACTIONS OF THE METHANOLIC EXTRACT OF ANTIGONON LEPTOPUS (HOOK & ARN.)
Journal Title: International Journal of Pharmacognosy - Year 2018, Vol 5, Issue 4
Abstract
Antigonon leptopus Hook & Arn. (family Polygonaceae), also called: chain of love, Queen’s wreath and Mexican creeper is a fast growing vine with stems reaching up to 20 feet long. It has heart-shaped, green leaves climbing by tendrils which wrap around many types of the supports. It is native to Mexico and commonly found in tropical Asia, Africa, the Caribbean and the Americas. It possess anti-coagulant activity, analgesic, antithrombin, anti-inflammatory, antidiabetic and anti-depressant activities. Aerial parts of the vine have been used as hepatoprotective and for spleen disorders. During the current study, GC-MS experiment was conducted on both the methylene chloride and n-butanol fractions of the methanolic extract of the aerial parts of the vine. Results revealed the identification of total thirty five (35) and thirty seven (37) compounds respectively in both fractions examined. Compounds were characterized by their retention times, mass spectra with comparison to online mass bank database. The presence of flavonoids, phenolic acids, coumarins and organic acids in both fractions examined may be responsible for its wide pharmacological actions.
Authors and Affiliations
Nelly Ashraf Ramadan
Keywords
Related Articles
- EP ID EP431968
- DOI -
- Views 79
- Downloads 0
EVALUATION OF ANTIDIABETIC ACTIVITY OF HETEROPHRAGMA QUADRILOCULARE (ROXB.) K. SCHUM. LEAVES
Heterophragma quadriloculare (Roxb.) K. Schum. (HQ) belongs to Bignoneace family and known as Warras. Usage of HQ plant in diabetes has been claimed traditionally but scientific documentation is not yet available. So it...
A NEW NEO-CLERODANE DITERPENOID FROM TEUCRIUM POLIUM LINN.
Teucrium polium L. is a member of the Lamiaceae family and is represented in the Flora of Syria by two variety: Teucrium polium var. angusti folium and Teucrium polium var. mollissimum. Teucrium polium is a wild-growing...
PREPARATION AND EVALUATION OF IMMEDIATE RELEASE GLICLAZIDE TABLET USING SUPER DISINTEGRANTS
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets we...
INHIBITION OF AMYLIN FIBRIL FORMATION AND PROTECTION OF ISLET β-CELLS BY MEDICINAL PLANTS
Misfolding of some proteins, their self-assembly into insoluble amyloid structures underlies many diseases, constituting a group of amyloid-related pathology. Fibrillation of peptide hormone of the pancreas, amylin, is c...
PHARMACOGNOSTIC ACCOUNT AND PHYTOCHEMICAL STUDIES OF MORINGA OLEIFERA LINN.
Moringa oleifera, an important medicinal plant is one of the most widely cultivated species of the family Moringaceae. It is highly valued from time immemorial because of its vast medicinal properties. The present articl...