Granulomatous inflammation in lymph nodes draining cancer: significant association or just coincidence- Diagnostic dilemma

Journal Title: IP Journal of Diagnostic Pathology and Oncology - Year 2018, Vol 3, Issue 4

Abstract

Causes of granulomatous inflammation are broadly divided into infective and non infective Infective causes Includes myocbacterial fungal or parasitic origin Non infective includes Foreign body granuloma sarcoidosis crohns disease Granuloma formation seen in cancer patients may be due to previous chemotherapy or radiation therapy However in many cases mechanism in granuloma formation and its therapeutic outcome in cancer patients remains unknown Careful scrutiny in all cases is required where coexisting malignancy was suspected along with granuloma formation in lymph nodes draining cancers Exact cause of granuloma formation in lymph nodes draining cancer remains unknown however immunological reaction to tumour antigens is proposed theory These granuloma may represent impending metastasis or already existing metastasis in patients who received neoadjuvant chemoradiationKeywords Granuloma Lymph nodes Metastasis Chemoradiation

Authors and Affiliations

Rakesh Kumar J. Ajmera, Rohini Shewale, Hemant Kokandakar

Keywords

Related Articles

ABC like DLBCL

Diffuse large B-cell lymphoma [DLBCL] is the most frequently-occurring lymphoma, accounting for an estimated 35% of all lymphoma cases worldwide. This heterogeneous disease has a complex classification, and if left untre...

Correlation of VEGF and HIF-1α in breast carcinoma (an immunohistochemical study)

Introduction By 2030 the incidence of breast cancer in India will increase to around 200000 per year During tumor growth angiogenesis is induced by many stimuli Reduced oxygen stimulates hypoxia induced factor 1 alpha HI...

Clinicopathological profile of neuroendocrine tumors of gastrointestinal tract

Introduction Neuroendocrine neoplasms are derived predominately from enterochromaffin or Kulchitsky39s cells The estimated prevalence of neuroendocrine tumors NET is 1 to 2 cases per 100000 people of which gastrointestin...

Clinicohistological correlation of psoriasis and immunohistochemical expression of Ki 67

Skin is considered as the largest organ of the body. Psoriasis is a chronic papillosquamous disorder of skin affecting 1-2% of population in all geographic areas.(4) There is a seven fold increase in the field of epiderm...

Epidermal Cyst with Malignant Transformation: A case report

Epidermal cysts are the commonest tumors of the skin. Malignant tumor arising from a cyst is extremely rare. A 30 years old male patient presented to surgical OPD with a cystic swelling over the forehead of 3 years durat...

Download PDF file
  • EP ID EP482793
  • DOI 10.18231/2581-3706.2018.0060
  • Views 105
  • Downloads 0

How To Cite

Rakesh Kumar J. Ajmera, Rohini Shewale, Hemant Kokandakar (2018). Granulomatous inflammation in lymph nodes draining cancer: significant association or just coincidence- Diagnostic dilemma. IP Journal of Diagnostic Pathology and Oncology, 3(4), 295-298. https://europub.co.uk./articles/-A-482793