GREEN SYNTHESIS AND CHARACTERIZATION OF SILVER NANOPARTICLES FROM AQUEOUS EXTRACT OF BASELLA ALBA AND THEIR IN-VITRO ANTIOXIDANT POTENTIALS
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2014, Vol 6, Issue 10
Abstract
Objective: To synthesize silver nanoparticles (AgNps) from Basella alba(B. alba) aqueous extract using 3 mM AgNO3 solution, to characterize the resulted AgNps and also to study the antioxidant activity by DPPH and reducing assay.Methods: 150 ml of aqueous extract was mixed with 600 ml of 3 mM silver nitrate solutions and kept at room temperature for 1hr. A change from straw yellow to golden yellow was observed and absorption spectra were obtained by UV-VIS spectrometer. The resulted nanoparticles (NPs) were characterized by FT-IR spectrum, SEM-EDS, TEM and XPS techniques. The purity and nature of the particles were observed through TG-DSC analysis. Further, Antioxidant activity was performed by DPPH (2, 2-diphenyl-1-picrylhydrazyl) method and by Ferric chloride reducing assay.Results: UV-Vis spectral analysis shows a maximum absorption peak at 435 nm. FT-IR spectrum indicated the formation of reducing and capping agents in AgNps. The synthesized silver nanoparticles was spherical in shape and its size ranges from 22.6 to 25 nm. The synthesized silver nanoparticles possess excellent antioxidant activity by various methods. The phenol carboxylic acid present in B. alba leaf extract acted as a reducing agent which was identified by HPTLC technique. A Protein present in the B. alba extract was responsible for the capping of bio-reduced silver nanoparticles. Conclusion: It has been demonstrated that Basella alba plant extract could be used as a proficient green reducing agent for the synthesis of AgNPs. Further studies will be focused towards the mass scale production of formulation.Â
Authors and Affiliations
Niraimathi Kl, R. Lavanya, V. Sudha, P. Brindha
Keywords
Related Articles
- EP ID EP579472
- DOI -
- Views 56
- Downloads 0
A CASE OF HYPOTHYROIDISM INDUCED RECURRENT DEPRESSIVE DISORDER
Recurrent depressive disorder is a lifelong illness with relapses and remissions. The aetiology is biopsychosocial, genetic factors contributing and life stressors exaggerating the disease. Due to recurrent episodes the...
ANTIDYSLIPIDEMIC ACTIVITY OF KATUK LEAVES SAPONINS FRACTION (SAUROPUS ANDROGYNUS (L.) MERR) IN RATS INDUCED WITH FAT-RICH DIET
Objective: The present study was to evaluate the anti dyslipidemic activity and the atherogenic indicator of saponin compound from katuk leaves (Sauropus androgynus (L).Methods: This compound separated from Katuk leaves...
EVALUATION OF PHYTOCHEMICAL AND ANTIBACTERIAL PROPERTIES OF CALOTROPIS PROCERA (AIT) R. BR. LEAVES
Objective: The correlation of phytochemical and antibacterial attributes of Calotropis procera leaves with an intent to understand its potential for application in different clinical investigations. Methods: The differen...
INJECTABLE CEPHALOSPORINS USEIN VIETNAMESE HOSPITALS:A DESCRIPTIVE CROSS-SECTIONAL MULTICENTER STUDY
Objective: The objective of this research was to investigate the use of injectable cephalosporins for inpatients at eleven hospitals in An-Giang province, Vietnam.Methods: This cross-sectional multicenter study was condu...
SYNTHESIS AND DOCKING STUDIES OF 2-(NITROOXY) ETHYL-4-(2-(SUBSTITUTED PHENYL)-4-(SUBSTITUTE DPHENYL)-1H-IMIDAZOL-1-YL) BENZOATE AS ANTI-INFLAMMATORY, ANALGESIC AND NITRIC OXIDE RELEASING AGENTS
Objective: The objective of the present study was to develop potent and non toxic Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) by using heterocyclic nuclei and having Nitric Oxide releasing group.Methods: The compounds...