H1N1 Vaccine May Cause Hepatic Dysfunction

Abstract

Aim: In this case, we reported an unusual side effect which may be related to adjuvant H1N1 vaccine. Case Report: A sixty-three year-old man was admitted to our hospital with fever, nausea, vomiting and fatigue 15 days after his immunization against H1N1 virus. Laboratory findings were, aspartate aminotransferase (AST):620 U/L, alanine aminotransferase (ALT): 561 U/L, alkaline phosphatase (ALP):152 U/L, gamma-glutamyl transferase (GGT): 482 U/L. His clinical symptoms resolved within two days. His elevated liver function tests reduced gradually and completely normalized on day 6 of his hospitalization. Discussion and Conclusion: H1N1 vaccination may cause increases in liver enzymes and it should be considered in differential diagnosis of abnormal liver function tests.

Authors and Affiliations

Ferdane Sapmaz, Sebahat Başyiğit

Keywords

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  • EP ID EP343826
  • DOI 10.9734/IJMPCR/2015/18807
  • Views 99
  • Downloads 0

How To Cite

Ferdane Sapmaz, Sebahat Başyiğit (2015). H1N1 Vaccine May Cause Hepatic Dysfunction. International Journal of Medical and Pharmaceutical Case Reports, 5(2), 1-3. https://europub.co.uk./articles/-A-343826