Haematologic and Biochemical Indices of Plasmodium falciparum Infected Inhabitants of Owerri, Imo State, Nigeria
Journal Title: Scientific Journal of Biological Sciences - Year 2013, Vol 2, Issue 8
Abstract
The present study seeks to investigate changesin haematologic and biochemical indices of moderately P. falciparum infectedmale inhabitants of Owerri Municipality. Haematologic and biochemical indiceswere estimated by spectrophotometric methods. Haemoglobin concentrations ofmalarious subjects within age brackets of 11-20 and 21-31 years were belowreference interval; [Hb]M;11-21 years = 10.53±0.23 g/dL (p > 0.05); [Hb] M;21-31 years = 11.51±1.10 g/dL (p > 0.05). There was no significantdifference (p < 0.05) in erythrocyte sedimentation rate (ESR) between thetwo malarious groups; ESRM; 11-20 years = 29.80±0.74 mm/h; ESRM; 21-31 years =26.51±1.42 mm/h. Packed cell volume (PCV) of malarious subject gave thefollowing values: PCV%M; 11-20 years = 26.82±0.78; PCV%M; 21-31 years =25.82±0.78; p < 0.05. Serum white blood cell count (WBC) was raised inmalarious subjects compared to control groups (p < 0.05) excerpt withWBC×103M; 21-30 years = 13.77±3.95; p < 0.05. Serum albumin was lower inmalarious subjects; [Albumin]M; 11-20 years = 4.70±0.05 mg/dL and [Albumin]M;21-31 years = 4.31±0.09 mg/dL; p < 0.05, whereas, serum creatinineconcentrations of malarious subjects gave higher values: [Creatinine]M; 11-20years = 0.88±0.71 mg/dL and [Creatinine]M; 21-31 years = 1.14±0.42 mg/dL; p< 0.05. Serum urea concentrations of malarious subjects were significantly(p > 0.05) higher than the corresponding non-malarious age group. Serumfasting blood sugar (FBS) was significantly (p > 0.05) lower in malariousgroups compared to corresponding non-malarious subjects. Specifically, [FBS]M;11-20 years = 63.34±1.66 mg/dL and [FBS]M; 21-31 years = 69.45±1.25 mg/dL; p> 0.05. Subjects with moderate malaria infection showed symptoms of anaemia,alterations in nitrogen and carbohydrate metabolism,exemplified by raised serum level of urea and low level of FBS.
Authors and Affiliations
J. O. Akaninwor| Department of Biochemistry, University of Port-Harcourt, Port-Harcourt, Nigeria., E. B. Essien| Department of Biochemistry, Imo State University, Owerri, Nigeria., P. C. Chikezie*| Department of Biochemistry, Imo State University, Owerri, Nigeria., R. T. Okpara| Department of Biochemistry, University of Port-Harcourt, Port-Harcourt, Nigeria.
Keywords
Related Articles
- EP ID EP1089
- DOI 10.14196/sjbs.v2i8.938
- Views 480
- Downloads 27
Promoting micro livestock farming to enhance animal product supply in sub saharan Africa
In Sub Saharan Africa the demand for food of animal origin is growing much faster than production due to improved health education, higher income per capita and ever increasing population growth. Production of animal pr...
Evaluation of the response of Clibanarius africanus (Decapoda: Paguridae) to crude oil in static bioassay
The acute toxicity of Nigeria Bonny light crude oil against hermit crab, Cliabanarius africanus of a tidal creek, Eastern Obolo, Akwa Ibom State, Nigeria was investigated in the laboratory under static bioassay. The...
Ensuring equitable resource allocation and gender sensitive policies in supporting food production and security in Southern Africa
Gender disparities in resource allocation and non gender responsive policies are important constraint to increasing food production and security in Southern Africa. The discussion attempt to explore the role of equitabl...
Study of genetic variation and phenetic relationships in some vulnerable taxa from Indian sundarbans following RAPD marker analysis
The mangrove ecosystem plays an important role in maintaining coastal ecological balance and is also one of the most highly productive and dynamic ecosystems to mankind, providing food, livelihood and ecological security...
Abiotic factors and anti-reproductive action of bait containing eugenol against Lymnaea acuminata
The effect of abiotic factor (temperature, pH, dissolved oxygen, carbon dioxide) on the reproduction of snail L. acuminata fed to bait containing 40% and 80% of 24h LC50 eugenol have been reported in this paper. Feeding...