Haemodynamic Changes and Blood Sugar Levels Before and After Induction of General Anaesthesia with Thiopentone Sodium and Etomidate - A Comparative Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
The aim of this study is to compare the efficacy of two different anesthesia induction approach i.e Inj Thiopentone sodium and Inj. Etomidate in maintaining hemodynamic stability during induction and following endotracheal intubation in elective surgery. After obtaining Ethical committee clearance, 90 patients aged 15 to 60 years of either sex or ASA physical status I or II scheduled for elective surgery under general anaesthesia were taken for study. Written and informed consent was taken from the patients. This was conducted at Kamineni Academy of Medical sciences and research centre, Hyderabad. The patients were randomly placed into two groups. Group T induced with Inj.Thiopentone sodium (5 mg/kg) intravenous, Group II with Inj. Etomidate (0.3 mg/kg) intravenously. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP) and oxygen saturation (SPO2) were noted at different time interval. Heart rate in all study groups decreases after induction and it was more in group T compared to group E and after intubation HR increases in two groups but this increase is greater in group E than groupT. MAP among all three groups decreases after induction and it was more in group T than group E and Significant increase in MAP was seen at 1 min after intubation in all three groups but this increase was not sustained and returned to baseline in group II. The etomidate has better hemodynamic stability than thiopentone sodium at 1 min after intubation and was equally stable at other points of time.
Authors and Affiliations
Dr. Jhoshna Deverakonda, Dr. Somavarapu Sarwesh Kumar, Dr. Ramu Valluri
Keywords
Related Articles
- EP ID EP475790
- DOI -
- Views 53
- Downloads 0
Accuracy of Prediction of Stature Based on Hand and Foot Dimension in Bhutanese Students
Stature is the height of the person in the upright posture and a useful anthropometric parameter for identification of an individual the present study was conducted to predict better parameter in the estimation of statur...
A study of correlation between the environmental factors and occurrence of Influenza an H1N1cases in Baroda district
The Influenza a H1N1 in humans can be a mild illness or in some people it may result in serious, even life-threatening complications such as pneumonia, acute bronchitis, worsening of chronic conditions, respiratory failu...
Spectrum of Non Neoplastic Skin Diseases: A Histopathology Based Clinicopathological Correlation Study
Skin, the largest organ of our body, is extraordinarily vibrant with regard to the diversity and complexity of the protective functions it serves. Many skin diseases can be diagnosed by a simple clinical examination, but...
Iniencephaly with Anencephaly: Case Report
Iniencephaly is an extremely rare neural tube defect characterized by the triad of fixed retroflexion of the head, variable degrees of cervical lordosis and dysraphism, and an occipital bone defect involving the foramen...
Microbiological Infectivity in Medical Laboratory Benghazi, Libya
Abstract: We surveyed environmental surfaces in our clinical microbiology laboratory one at Reference laboratory, Benghazi and other at Pediatric Hospital Laboratory to determine bacterial contamination during a routine...