Halitosis Treatment Through the Administration of Antibiotic-Resistant Probiotic Lactic Yeast Kluyveromyces marxianus fragilis B0399 (K-B0399)
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2018, Vol 12, Issue 1
Abstract
Halitosis (oral malodour) is a common problem, which creates severe social and relational difficulties. The most popular approach is to mask the smell, without considering the bacterial aetiology of the problem. The aim of this study is to demonstrate the efficacy of the administration of encapsulated Kluyveromyces marxianus B0399 by measuring the amount of VSC (Volatile Sulphur Compounds) with follow-up at 7 and 14 days. At the end of treatment, about 91% of patients did not present halitosis. The protocol did not consider any oral hygiene treatment. The drug is in capsule form with a shell. Therefore, results were achieved with a direct action on the intestine, not at an oral level. In conclusion, this study proves that, besides the rebalancing effect of probiotics in dysbiosis, there are many immunological implications on GALT (Gut Associated Lymphoid Tissue).Halitosis is an organic disorder that manifests as unpleasant smell that comes from the mouth during respiration or during simple eloquence. Causes may result from imbalance of the oral cavity microbiota such as metabolic disorders, disturbed commensal microflora equilibrium, use of certain types of foods and some respiratory infections [1,2]. Everyone in life has suffered from halitosis, so much so that it has been discussed since Greek and Roman times. More detailed studies have only been done since the beginning of the last century. Miyazaki et al. [3] classified halitosis in three categories: physiological or transient bad breath, true halitosis and halitophobia or imaginary halitosis. Physiological halitosis is a situation normally present in specific situations and that goes away by itself, thus without a pathological significance
Authors and Affiliations
Cecchini F, Nobili A, Zanvit A, Miclavez A
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