Hand radiograms as an alternative for bone mass screening in cystic fibrosis
Journal Title: Progress in Health Sciences - Year 2013, Vol 3, Issue 1
Abstract
Purpose: Cystic fibrosis (CF) is a genetic, metabolic disease. Long-term therapy often leads to inappropriate calcification of bones. Dual X-ray absorptiometry (DXA) is considered a „gold-standard” for bone mineral density (BMD) assessment, but high usage costs can limit its availability. This paper compares two methods for BMD assessment in CF patients: hand radiograms method and densitometry using DXA method. Materials and methods: The study was performed in a group of 26 CF patients (10F, 16M), aged 7-30 years. In all cases, DXA measurements were performed, along with bone mass assessment using DENSY2004 system for digital assessment of hand radiograms. Stepwise binary logistic regression was used to examine the contribution of bone age, BMI, Cole's index and hand radiograms parameters to low BMD expressed as Z-score ≤-1SD. Results: Statistical analysis of the gathered data revealed that hand radiograms method allow for estimation of Z-score below -1SD with accuracy of 84.62% comparing to DXA. Sensitivity and specificity of this estimation in the studied group of CF patients was 86.67% and 81.82%. Conclusions: Hand radiograms method has good accuracy, sensitivity and specificity; therefore, it can be an alternative for DXA in BMD assessment. It can be implemented in chronic diseases affecting BMD like cystic fibrosis.
Authors and Affiliations
A. Minarowska, Ł. Minarowski Ł. , W. Tomalak, J. Zając, A. J. Milewska, B. Kirpsza, Sł. D. Szajda, E. Chyczewska
Keywords
Related Articles
- EP ID EP69539
- DOI -
- Views 145
- Downloads 0
The topic about midwifery healthcare in the event of a mass terrorist attack among Keynote Presentations at the International Conference on „Nursing Diagnosis & Midwifery 2018”
The International Conference "Nursing Diagnosis & Midwifery 2018" held on 10-11 September 2018 in Prague (Czech Republic) was important for the international environment of midwives and nurses. The Event gathered represe...
Sociology and psychology – the scope of cooperation in studying the problems of health and disease
The aim of this dissertation is to identify the scope of convergence of sociology and psychology with special attention to the areas which are especially essential in the analysis of phenomena connected with human health...
Tarsal tunnel syndrome in patients with lumbar disc degeneration: a preliminary study
Purpose: An idea of "double-crush syndrome", introduced by Upton and McComas, is a concept considered for cervical disc disease and the carpal tunnel syndrome. Similar hypothesis can be put forward for lumbar disc...
Giant lipoma of the face and neck – a case report
A 65-year-old patient with multiple lipomas of various body regions presented to the Maxillofacial Surgery Clinic in Bialystok to treat a giant lipoma of the face and neck. After undergoing in-depth diagnostics (CT of th...
Predictive roles of coping and resilience for the perceived stress in nurses
Introduction: Nursing profession is physically and emotionally demandingPurpose:To determine the relationship between coping strategies and resilience, as well as perceived stress among nurses.Materials and methods: The...