Headaches and hormonal disorders
Journal Title: Postępy Nauk Medycznych - Year 2010, Vol 23, Issue 8
Abstract
Some endocrinological causes of headaches are well known, others are less known in daily practice. Thirty-three to seventy-two percent of pituitary adenomas induce headache. Headache is the first symptom in about 11% of women and in about 15% of men. Headache seems to be more frequent in prolactin-secreting adenomas than in the GH-secreting ones. The patophysiology of pituitary-associated headache is unknown, although structural and functional features of the tumour are proposed mechanisms. Mass effect of the tumor is not always correlated to the presence or intensity of the headache and biochemical activity may be important in some forms of pituitary tumor-associated headache. Also the association between hypothyroidism and tension-type headache has been reported (30% of patients), but the role of thyroid dysfunction in headaches patogenesis remains uncertain. Phaechromocytoma can be manifested only as a thunderclap headache. Migraine, as well as, a number of other primary headaches, are more common in women. Predilection for migraine attacks fluctuate with changes in the female reproductive life-cycle including menarche, menstruation, pregnancy, peri- and post-menopausal phases. Also, taking exogenous estrogen as oral contraceptive pills and estrogen replacement therapies may change the intensity of migraine. The aim of this study is to analyze the presence of headache and their characteristics in neuroendocrine disorders.
Authors and Affiliations
Anna Zduńska, Joanna Cegielska, Jan Kochanowski
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