HEALTH-RELATED QUALITY OF LIFE IN CHILDREN WITH SEVERE HEMOPHILIA A IN UKRAINE: AGE-RELATED FEATURES ON THE INFLUENCE OF THE SUBSTITUTION TREATMENT METHODS

Journal Title: INTERNATIONAL ACADEMY JOURNAL "Web of Scholar" - Year 2018, Vol 2, Issue 7

Abstract

Objective: study the influence of the substitution treatment methods on the health-related quality of life (HRQoL) in children with severe hemophilia А (HА) in different age groups. Materials and methods: HRQoL is examined in 105 children of three age groups (Group І (n=31) – children 4-7 years, ІІ (n=46) – 8-12 years, ІІІ (n=28) – 13-16 years) with HA using Haemo-QoL questionnaire. The indicators of HRQoL were compared between different age groups, undergoing Prophylaxis Treatment (PT), Treatment “On-demand” (OD) and ІТІ (immune tolerance induction) therapy. Results: The worst HRQoL in children of all groups is manifested in the course of ІТІ. When comparing HRQoL in the course of PT and OD it was found that in Group І the best HRQoL is in the course of OD, in Group ІІ it does not differ, while in Group ІІІ in the course of PT general HRQoL is the best, but such a difference was not statistically significant (SS), at SS the comparison of HRQoL of the most part of segments of psycho-social functioning. Conclusions: it was proved that HRQoL in children with HA depends on the treatment method with age-related features of such dependence.

Authors and Affiliations

A. I. Markin, L. Ya. Dubey

Keywords

Related Articles

INTELLIGENT TECHNOLOGIES OF FUNCTIONAL DIAGNOSIS AND MODELING OF SURGERY OPERATIONS

Thus, the authors proposed intellectual technologies for modeling and computer planning of surgical interventions on the basis of complex processing and analysis of diagnostic data implemented in rhinolaryngology, otolog...

MASS EXCHANGE IN APPARATUS WITH REGULAR PACKINGS AND THEIR CALCULATION

The paper presents data on the investigation of mass-transfer coefficients in the gas and liquid phases for three kinds of packing elements. Plate, ball and tubular packing elements. The dependences of the coefficients o...

THE FAMILY AS A FACTOR OF THE ETHNIC SELF-CONSCIOUSNESS FORMATION OF THE PERSONALITY (CROSS-CULTURAL STUDY)

The article deals with the study of the ethnopsychological peculiarities of the family influence on the formation of the ethnic self-consciousness among teenagers and adolescents As a result of the empirical research, it...

НЕВЕРБАЛЬНЫЕ КОМПОНЕНТЫ КОММУНИКАЦИИ В ПРОИЗВЕДЕНИЯХ КАЗАХСКИХ ПИСАТЕЛЕЙ И ОСОБЕННОСТИ ИХ ПЕРЕВОДА

The article considers non-verbal components of communication in the literary texts of Kazakh writers and identifies the features of their translation. For the purposes of contrastive research in non-verbal components of...

FEATURES OF WORK WITH PRIMARY SCHOOL CHILDREN WITH SPEECH DISORDERS IN SCHOOL

In the article the author emphasizes that current trends of schooling demand the quality of students’ knowledge, the foundations of which are laid at the beginning of their study in school. It is noted that the level of...

Download PDF file
  • EP ID EP396882
  • DOI 10.31435/rsglobal_wos/12072018/5983
  • Views 145
  • Downloads 0

How To Cite

A. I. Markin, L. Ya. Dubey (2018). HEALTH-RELATED QUALITY OF LIFE IN CHILDREN WITH SEVERE HEMOPHILIA A IN UKRAINE: AGE-RELATED FEATURES ON THE INFLUENCE OF THE SUBSTITUTION TREATMENT METHODS. INTERNATIONAL ACADEMY JOURNAL "Web of Scholar", 2(7), 15-19. https://europub.co.uk./articles/-A-396882