Health-related quality of life in oropharyngeal cancer survivors – a population-based study
Journal Title: Otolaryngologia Polska - Year 2018, Vol 72, Issue 2
Abstract
Objective: The aim of this study was to compare QoL of oropharyngeal cancer survivors who had received different treatments. Subjects and methods: We contacted 954 survivors. Each survivor received the QoL questionnaires EORTC QLQ-C30 and EORTC QLQ-H&N35. Results: A total of 263 survivors completed the questionnaires (28% responses). Forty-five of them had undergone surgery, 20 had received definitive radiotherapy or chemo-radiotherapy, 85 surgery plus adjuvant radiotherapy, and 111 surgery plus adjuvant chemo-radiotherapy. Survivors who had received adjuvant radiotherapy and surgery reported significantly more problems with swallowing (B=13.43 [95% Confidence Interval (CI) 1.83-25.03]), senses (B=24,91 [CI 11.86-37.97]), eating (B=16.91 [CI 3.46-30.36]), dry mouth (B=26.42 [CI 12.17-40.67]), sticky saliva (B=22.37 [CI 6.23-38.50]) and nutritional supplements (B=18.59 [CI 0.62-36.56]) than those who had received surgery only. Survivors who had received adjuvant chemo-radiotherapy and surgery reported significantly many more problems with dry mouth (B=34.15 [CI 18.91-49.39]) and sticky saliva (B=22.90 [CI 5.65-40.16]), and fewer problems with physical functioning (B=-12.07 [CI 0.49-23-64]). Conclusion: Survivors who participated in this survey and who had undergone surgery alone reported in some head- and neck-specific domains a better health-related quality of life than patients who had undergone multi-modal treatment or adjuvant radiotherapy.<br/><br/>
Authors and Affiliations
Thomas Guenzel, U. Walliczek-Dworschak, A. Teymoortash, S. Singer, M. Eichler, T. Wilhelm
Keywords
Related Articles
- EP ID EP275835
- DOI 10.5604/01.3001.0011.7249
- Views 90
- Downloads 0
Ekspresja receptora CD27 na limfocytach T i B w tkance przerosłych migdałków gardłowych u dzieci chorych na wysiękowe zapalenie ucha środkowego
Introduction: Adenoid has particular meaning to develop of immunological response to inflammations in upper respiratory inclusive middle ear. The mining of antigen CD27 on lymphocytes T and B in creation of memory cells...
Coexistence of acoustic neuroma and pineal region tumor in patient with sudden deafness
Introduction. Acoustic neuroma usually presents as an unilateral tumor, seldom – bilateral and rarely in coexistence with other central nervous system neoplasms. The following paper reports such a case of a 21-year-old m...
Wiek a powikłania po laryngektomii
Between 1989–1999, 573 patients (501 male and 72 female) with laryngeal cancer underwent laryngectomy in the Otolaryngological Clinic of the Medical University in Bydgoszcz. The age varied from 32 to 88 years (mean age –...
Praktyczne aspekty interakcji leków w farmakoterapii otolaryngologicznej, czyli 7 grzechów głównych leczenia farmakologicznego w praktyce lekarza otolaryngologa
Interakcje leków stanowią coraz większy problem w praktyce otolaryngologicznej. Stosowanie leków u pacjentów stosujących politerapię generuje ryzyko niekorzystnych interakcji leków, co wymaga specjalistycznej wiedzy w ty...
Hearing improvement in patients operated on chronic otitis media