Hematologic Analysis of Pancytopenia and Correlation with Bone Marrow Findings: Study in a Tertiary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 10
Abstract
Background: Pancytopenia is one of the most common haematological disorders, which is characterized by decrease in all the formed elements of blood. Pancytopenia occurs either due to certain primary conditions affecting the bone marrow or involvement of bone marrow secondarily by various systemic pathological process. Objectives: The main objectives of the study are to evaluate the incidence and pattern of pancytopenia by analyzing the haematological data available during one year in the central laboratory of a tertiary care hospital in Navi Mumbai and to correlate the haematological findings with bone marrow findings. Methods: The present prospective study, consists of an analysis of haematological data over a period of one year and analysing the incidence and pattern of pancytopenia and to correlate the haematological findings with bone marrow findings. Results: In this study, 100 cases of Pancytopenia are diagnosed with an incidence of 0.47%. Bone marrow findings are available in only 15% cases of pancytopenia, and maximum incidence of pancytopenia, 5 cases (33.3%) is associated with chronic liver disease, followed by association with megaloblastic anaemia, 2 (13.3%) cases. In rest of the cases, definitive diagnosis of pancytopenia is not available, though the patients are being treated for various clinical conditions. Conclusion: The highest incidence of pancytopenia is found in age group of 40-70 years. Bone marrow findings confirmed the diagnosis in 15% cases, showing Dysmegakaryopoiesis maximum incidence of cases associated with erythroid hyperplasia with megaloblastoid changes and chronic liver disease accounted in 21 cases of pancytopenia.
Authors and Affiliations
Kalyani Mahore
Keywords
Related Articles
- EP ID EP529753
- DOI -
- Views 74
- Downloads 0
Gutka Facies in Oral Submucous Fibrosis – A Cross Sectional Study in Chennai
Introduction:“Gutka facies” is characteristically seen in patients with oral submucous fibrosis, a chronic progressive scarring disease of the oral mucosa which is recognized as a potentially malignant disorder Aim: To e...
Cervical Dystonia and Psychiatric Manifestations in Hypoparathyroidism Associated with Extensive Intracerebral Calcifications
Hypoparathyroidism can be associated with brain calcifications and varied neuropsychiatric manifestations. A 61 year old male presented with history of gradually progressive behavioural disturbances, initially diagnosed...
HIV Infection and Malignancy
HIV-infected individuals have an increased propensity to develop malignancy. The spectrum of neoplasia in these patients is changing, especially in developed portions of the world, where the widespread use of highly acti...
Mesh Migration Causing Strangulated Intestinal Obstruction After Umbilical Hernia Repair
Mesh migration following hernia repair is an uncommon complication, leading to erosion, infection, fistula or obstruction. Migration can occur because of primary factors like inadequate fixation or can be secondary due t...
A Rare Presentation of Chikungunya in Infant- A Case Report
We have discussed about an infant who contracted the disease - Chikungunya, a resident of endemic area. He had high grade fever followed by rash. His serum was tested for both Dengue and Chikungunya fever. In this case,...