Hemophagocytic Lymphohistiocytosis: An Uncommon Clinical Syndrome

Journal Title: IP International Journal of Medical Paediatrics and Oncology - Year 2016, Vol 2, Issue 1

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is an acute life threatening clinical syndrome that is characterized by an uncontrolled activation and proliferation of the cells of monocyte/ macrophage lineage secondary to various inherited or acquired disorders of immune function1,2. This rare clinico-pathological syndrome is characterized by uncontrolled systemic hyperinflammation caused by hyper-cytokinemia driven by an ineffective immune system that has gone haywire3

Authors and Affiliations

Waseem Iqbal, Karuna Kumar, Ngangbam Sonamani, Shobha Badiger, Tadele Hailu, Sunil Bhat

Keywords

Related Articles

Effectiveness of music therapy on biophysiological and psychological outcomes during chemotherapy among patients with cancer- A pilot study

The diagnosis and the treatment for cancer are significant stressors for the patients. Chemotherapy is often considered the most stressful of the treatment modalities primarily as a result of the myriad of side effects t...

Study of prevalence and risk factors associated with respiratory illness in children admitted in a teaching hospital in rural Telangana

Introduction Acute respiratory tract illness is common in children especially under 5 years of age Poor hygiene poor sanitation overcrowding are the major risk factors for respiratory infections in paediatric age groupAi...

Gestational trophoblastic disease (GTD)

Gestational trophoblastic disease comprises hydatidiform mole (complete and partial) and gestational trophoblastic neoplasia. The epidemiology, clinical features, and diagnosis of each of these trophoblastic disease type...

Rapidly growing brain tumor in a newborn considered to be teratoma: A rare case report

Teratomas constitute approximately 0.2% of all intracranial tumors.[1] They mostly occur in children during the first decade and grow frequently in the midline region.[3] Here, we report a rare case of posterior fossa im...

Neonatal positivity of CRP test in early onset neoanatal sepsis in relation to duration of PROM vs PROM delivery Interval (PDI)

Aim: To know, which one, PROM duration or PDI is in high risk for CRP positive early onset neonatal sepsis to start antibiotic in treatment to prevent perinatal morbidity and mortality. Methodology: Total 150 newborn cas...

Download PDF file
  • EP ID EP242762
  • DOI -
  • Views 149
  • Downloads 0

How To Cite

Waseem Iqbal, Karuna Kumar, Ngangbam Sonamani, Shobha Badiger, Tadele Hailu, Sunil Bhat (2016). Hemophagocytic Lymphohistiocytosis: An Uncommon Clinical Syndrome. IP International Journal of Medical Paediatrics and Oncology, 2(1), 27-32. https://europub.co.uk./articles/-A-242762