Hemostasis Management during Adult Extracorporeal Membrane Oxygenation: A Shot in the Dark?
Journal Title: Research and Practice in Anesthesiology – Open Journal - Year 2016, Vol 1, Issue 1
Abstract
Extracorporeal membrane oxygenation (ECMO) has been used increasingly in adult patients with cardiopulmonary failure.1 According to the Extracorporeal Life Support Organization’s (ELSO’s) 2012 report over 51,000 patients have received ECMO. Most cases are for neonates; however, an increasing proportion is for adults.2 ECMO is a unique life saving therapy, but many patients experience complications including: hemolysis, systemic thromboembolism, neurologic complications, and bleeding.3 We previously reported that up to 56% of patients experience at least one significant bleeding event during ECMO and the rate of serious bleeding events is approximately 10 per 100 ECMO days.4 Our data also suggest that bleeding events and the amount of transfusion on ECMO are associated with decreased survival.
Authors and Affiliations
Michael Mazzeffi
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