Heparin induced thrombocytopenia as a complication of coronary artery by-pass surgery - case report
Journal Title: Kardiochirurgia i Torakochirurgia Polska - Year 2006, Vol 3, Issue 1
Abstract
A 67-year-old woman with ischemic cardiomyopathy (EF=32%) was scheduled for elective coronary artery by-pass grafting surgery. The operation was performed on the beating heart (OPCAB). In the early postoperative period the syndrome of low cardiac output was diagnosed and intraaortic pump was inserted. The continuous infusion of unfractionated heparin was started. In a few postoperative days improvement in cardiac function was observed and intraaortic counterpulsation was terminated. Simultaneously the infusion of heparin was stopped and low molecular weight heparin was applied. On the 10th postoperative day an unexpected fall in platelet count was observed. Clinical signs of thrombosis were not present. The low molecular weight heparin treatment was discontinued and warfarin introduced. INR was kept below 3. The results of laboratory tests for heparin – induced thrombocytopenia antibodies were positive. After several days of treatment the platelet count returned within the normal range. Patients undergoing cardiac surgery are at risk of HIT. The reported incidence of postoperative antibody seroconversion in cardiac surgery patients ranges between 25-50%. The risk of developing clinical HIT is influenced by the heparin treatment.
Authors and Affiliations
Ewa Kucewicz-Czech, Jacek Kaczmarski, Waldemar Pakosiewicz, Roman Przybylski, Piotr Knapik, Marian Zembala
Keywords
Related Articles
- EP ID EP128770
- DOI -
- Views 82
- Downloads 0
Lung pathology following cardiopulmonary by-pass in patients with Down syndrome (DS) associated with atrioventricular septal defect (AVSD) (preliminary report)
In spite of progress, cardiopulmonary by-pass (CPB) still has a deteriorative effect on the lung. Surgical correction of AVSD improves compliance and respiratory function. However early extubation post operation, especia...
Relacja z XXII Dorocznego Kongresu Węgierskiego Towarzystwa Kardiochirurgicznego
Tissue engineering methods as a potential instrument used in treatment of circulatory system diseases
Tissue engineering as well as the cell culture techniques seem to be the promising perspective of alternative treatment of circulatory system diseases. Quite recently, mentioned methods have been still only in the phase...
Badanie wpływu niskoenergetycznego promieniowania laserowego na parametry hemodynamiczne izolowanego perfundowanego serca szczurzego poddanego niedokrwieniu – wyniki wstępne
Wstęp: Promieniowanie laserowe może modulować procesy biologiczne. Szczególne znaczenie wydaje się mieć jego wpływ na procesy zachodzące w mięśniu sercowym podczas niedokrwienia. Cel: Ocena wpływu niskoenergetycznego p...
Transcatheter closure of atrial septal defects - own experience after 502 procedures
Introduction: Percutaneous closure has became treatment of choice in selected cases of atrial septal defects type II (ASD). Aim: To show own experience in this field. Material and methods: Between 1997-2005 there were...