Hepatic Failure Resulting from Neonatal Thyrotoxicosis
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 5
Abstract
The objective was we report a case of jaundice, fulminant hepatic failure and pulmonary hypertension in premature baby caused by neonatal thyrotoxicosis. The Methods were We describe the clinical and laboratory findings relating to the case in Results A premature baby boy born to a primigravida mother by cesarean section was born by cesarean section at 31 weeks of gestation because of fetal tachycardia (heart rate: 190 beats/min). At birth, the patient presented with tachycardia (heart rate: 220–240 beats/min), respiratory distress, hepatomegaly and jaundice. The mother had mild exophthalmos and had undergone radio ablation for Graves’ disease 6 years prior to conception. The neonate was diagnosed as having neonatal thyrotoxicosis causing pulmonary hypertension and hepatic failure. The clinical condition of the neonate improved after treatment was initiated with carbimazole (1.5 mg/kg/day) and propranolol (2 mg/kg/day). The Conclusions To the best of our knowledge, our case is the first reported case of hepatic failure associated with neonatal thyrotoxicosis. Early recognition and treatment of neonatal thyrotoxicosis are crucial to avoid the associated complications, which include hepatic failure. Keywords: Premature baby, hepatic failure, neonatal thyrotoxicosis, Graves’ disease, thyroid-stimulating immunoglobulins, carbimazole
Authors and Affiliations
Najya A. Attia Attia, Yousef I. Marzouk, Adeeb Hashim Munshi
Keywords
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