Hepatic histological comparison between Acute Self-limiting Hepatitis A and Hepatitis E
Journal Title: Archives of Hepatitis Research - Year 2017, Vol 3, Issue 1
Abstract
Background: Histological findings of the liver in acute liver injury are basically affected by degree of liver damage. However, the differences in liver histology between acute self-limiting hepatitis A (AH-A) and hepatitis E (AH-E) have not yet been clarified. This study aimed to clarify the differences in histological findings of the liver between AH-A and AH-E. Methods: Fourteen patients with AH-A and 11 patients with AH-E matched with the period between the onset of AH and the performance of liver biopsy and with the degree of liver function impairment were studied. The activity grade and fibrosis stage were evaluated using the METAVIR scoring system and the semiquantitative scores using 9 items from histological findings: interface hepatitis, portal lymphocytes, portal neutrophils, lobular necrosis, lobular inflammation, steatosis, ballooning, Mallory bodies, and cholestasis.
Authors and Affiliations
Suzuki Kazuyuki, Tatemichi Yoshitoku, Yoshida Yuichi, Miyamoto Yasuhiro, Kuroda Hidekatsu, Miyasaka Akio, Takikawa Yasuhiro, Masuda Tomoyuki, Kumagai Ichiro, Okamoto Hiroaki
Keywords
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- EP ID EP559410
- DOI 10.17352/ahr.000016
- Views 54
- Downloads 0
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