HIGH SENSITIVITY C-REACTIVE PROTEIN IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ASTHMA- A PROSPECTIVE STUDY IN NORTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 18
Abstract
BACKGROUND High sensitivity C-reactive protein (hs-CRP) is an acute phase reactant with well documented sensitivity that is commonly used to diagnose infections and inflammatory conditions like COPD and Asthma. We wanted to study the plasma hs-CRP levels in patients of COPD and asthma. METHODS This is a prospective study conducted for a period of one year from Nov. 2017- Oct. 2018, conducted at GMC, Jammu, which is a tertiary care centre. In our study, out of 100 patients who were studied, 50 were male (50%) and 50 were female (50%) with male: female ratio of 1:1. RESULTS Thirty (30%) patients were asthmatics and seventy (70%) patients had COPD, with asthma to COPD ratio of 1:2.3. CONCLUSIONS High sensitivity C-reactive protein (CRP), which is an inflammatory marker, in the present study had a strong association with COPD and asthma both in males and females with interaction p-values in case of male asthmatics (0.003), female asthmatics (0.01), COPD males (0.001) and COPD females (0.001).
Authors and Affiliations
Vinod Kumar, Achint Singh, Ritu Bhagat, Roopali Jandyal
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