Histological and histochemical changes in placenta of diabetic pregnant females and its comparision with normal placenta
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2011, Vol 1, Issue 1
Abstract
Objective: To investigate the histological and histochemical changes in placenta of diabetic pregnant females and compare them with normal placenta. Methods: The histological and histochemical features of 60 placenta, 30 obtained from normal pregnant females and 30 from diabetic pregnant females, were studied. These placenta were obtained from Department of Obstetrics and Gynaecology, GSVM Medical College Kanpur and ERA ’s Lucknow Medical College and Hospital Lucknow. Results: On histological examination, the diabetic placenta showed increased syncytial knots, fibrinoid necrosis, trophoblastic basement membrane thickening, villous stromal fibrosis, villous oedema, crowding of villi, thickening of vessel wall and fibrin deposition. On histochemical study it was found that the PAS reactivity was stronger in diabetic placenta as compared to normal. Sudan Black reactivity was higher among diabetic placenta in comparison to normal placenta. Conclusions: It is concluded that distinct histological and histochemical changes could be seen in placenta of diabetic pregnant females.
Authors and Affiliations
Keywords
Related Articles
- EP ID EP234359
- DOI 10.1016/S2222-1808(11)60001-7
- Views 69
- Downloads 0
Sequencing and genetic analysis of hemagglutinin gene of H9 avian influenza viruses from Iran (2008 to 2011)
Objective: To survey on molecular characterization of Hemagglutinin( HA) gene in H9N2 viruses and determine genetic relationship between Iranian H9N2 viruses and other Asian viruses. Methods: Ten H9N2 viruses were isolat...
Hepatoprotective activity of Spillanthes acmella Extracts against CCl4- induced liver toxicity in rats
Objective: Hepato protective activity of Spillanthes acmella Extracts (70% ethanol, methanol, ethyl acetate and hexane) were investigated. Methods: Hepatoprotective activity was assessed against CCl4 induced liver intoxi...
Evaluation of antidiabetic property of Andrographis paniculata powder in high fat and sucrose-induced type-2 diabetic adult male rat
Objective: To evaluate the antidiabetic effect of the aerial part of Andrographis paniculata (A. paniculata) powder (500 mg/kg body weight) in high fat and sucrose-induced type-2 diabetic rat model. Methods: The fasting...
Natural medicines from plant source used for therapy of diabetes mellitus: An overview of its pharmacological aspects
Medicinal plants play an important role in the treatment of diabetes mellitus, especially in the developing countries due to their cost effectiveness. Diabetes mellitus, a metabolic disorder, is becoming a serious threat...
Laboratory evolution of the entomopathogenic fungus Beauveria bassiana against Anopheles stephensi larvae (Diptera: Culicidae)
Objective: To examine Beauveria bassiana (B. bassiana) fungus bioassay against the larval stages of Anopheles stephensi in Iran. Methods: The fungal suspension by the concentrations of 1伊1 09, 5伊1 08, 1 08, 5伊1 07 and...