HISTOMORPHOLOGICAL SPECTRUM OF CENTRAL NERVOUS SYSTEM TUMOURS- A THREE-YEAR RETROSPECTIVE DESCRIPTIVE STUDY IN A TERTIARY CARE CENTRE
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 43
Abstract
BACKGROUND CNS tumours are considered to be among the most notorious of all cancers. There is no accurate epidemiology of these CNS tumours in South India which makes policy making for tumour screening and early treatment difficult. The purpose of this study is to provide the spectrum of CNS tumours in a tertiary care centre in Chennai. MATERIALS AND METHODS This retrospective descriptive study was carried out at Department of Neuropathology, Madras Medical College, Chennai over a period of 3 years. A total of 890 cases who were diagnosed with CNS tumours on histopathology, registered between 2013 and 2015, were included and classified according to WHO 2007 classification with grading. Immunohistochemistry was done in needed cases. RESULTS A wide range of histopathological spectrum of CNS tumours was observed. Overall astrocytic tumours (36.1%) were the most common followed by meningeal tumours (24%) and metastatic tumours (9%). Males exceeded females in most of the CNS tumour types, except in meningeal tumours and tumours of cranial and paraspinal nerves. CONCLUSION Rising global trends of incidence of CNS tumours, irrespective of age and gender have been observed. The present study highlights the histological diversity in CNS tumours in both genders and all age groups. Based on this study, glioblastoma multiforme is the most common CNS tumour in our setup.
Authors and Affiliations
Narmadha R, Dhanalakshmi S, Priyadharshini M, Rajesh Natraj A. P, Subitha Subitha, Padmavathi S
Keywords
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- EP ID EP214513
- DOI 10.14260/Jemds/2017/728
- Views 60
- Downloads 0
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