Histomorphological spectrum of colonic biopsies: A two year study
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
Introduction Colonoscopy and accompanying mucosal biopsy is the diagnostic tool of choice in the evaluation of patients with colo rectal pathologies The objectives of this study were to study the histo morphological spectrum of colonoscopic biopsies to find age gender site distribution of these lesions and to correlate them with clinical presentation and colonoscopic diagnosisMaterials and Methods The study included all the colonoscopic biopsies received at Department of Pathology Kamineni Academy of Medical Sciences and Research Centre Hyderabad from January 2015 to December 2016 over a period of two yearsResults There were 198 colonoscopic biopsies during this period Two biopsies were inadequate for opinion and were excluded from the study All the colorectal resection specimens anal lesion were excluded from the study Out of total 196 biopsies 104 were nonneoplastic lesions 92 were neoplastic lesions Mean age of patients was 497 years with a male to female ratio of 161 Most common location of the lesion was rectum The most common presenting complaint for both nonneoplastic and neoplastic lesions was bleeding per rectum Nonspecific colitis was commonest nonneoplastic lesion followed by ulcerative colitis In the neoplastic lesions adenocarcinoma was the commonest subtype followed by adenomatous polypsConclusion Both neoplastic and nonneoplastic lesions equally affect colon Nonspecific colitis ulcerative colitis Crohns disease tuberculosis amoebic colitis eosinophilic enteritis hamartomatous and hyperplastic polyps were the various non neoplastic lesions encountered in our study Adenocarcinoma was the most common malignancy on colonic biopsies Carcinomas occurred at a later age than adenomas Colonscopic diagnosis correlated well with histopathology diagnosis in carcinomasKeywords Colonoscopy Mucosal biopsy Nonneoplastic lesions Neoplastic lesions Rectum Nonspecific colitis Adenocarcinoma
Authors and Affiliations
Ch. Geetha, M. Pavani, Shailaja Prabhala, A. K. Deshpande
Keywords
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- EP ID EP475494
- DOI 10.18231/2394-6792.2018.0045
- Views 59
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