Histopathological Analysis of Brain Tumours- A Seven Year Study from a Tertiary Care Centre in South India
Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 6
Abstract
Introduction: Tumours of central nervous system constitute 1%-2% of tumours in adults. The incidence of brain tumours has been reported to be around 3.9 and 3.0/one lac/year in males and females respectively. A few studies are available from India which show a lower incidence of brain tumours compared to the developed countries. Not much is known about the epidemiology of brain tumours in the population from South India. Aim: To identify the age groups, gender distribution, topography and different histological types of brain tumours. Materials and Methods: A total of 510 cases of brain tumours were identified over a period of seven years which were included in the present study. We retrieved the slides of these cases and reviewed them. Immunohistochemistry in required cases were done. Age and gender distribution, clinical presentation, site of tumour and histopathologic patterns with grade were noted and the data was analysed with SPSS software version 17.0. Results: Our analysis showed that most of the brain tumours occur between 40-60 years of age, with a male to female ratio of 0.9:1. Majority of cases involved dura and cerebral lobes except for the occipital lobe, and meningioma and glial tumours were the most common broad histological types. WHO grade IV tumours and metastasis were common in males compared to females. Conclusion: This study revealed the distribution of brain tumours in patients attending our institution. The results obtained were comparable with available worldwide data.
Authors and Affiliations
renu thambi, subitha Kandamuthan, sheeja SAINULA, letha VILASI, tinu ravi abraham, PK balakrishnan
Effect of Technique of Disinfection by Ultrasonic Nebulization on Accuracy of Vinyl Polysiloxane Impressions
ABSTRACT Introduction: To prevent cross-contamination, impressions should be properly disinfected after removing from the mouth. To be efficacious, a successful disinfection must maintain the physico-chemical properties...
Carcinoma Cervix Presenting as Ischaemic Stroke in Young Female: A Case Report and Review of Literature
Stroke is a disabling disease which increases the burden of already suffering cancer patients. Several mechanisms of stroke exist in cancer patients which includes - metastatic or non-metastatic such as coagulation disor...
Assessing the Safety and Clinical Impact of Thoracoscopic Lung Biopsy in Patients with Interstitial Lung Disease
Introduction: The clinical relevance of surgical lung biopsy in Interstitial Lung Disease (ILD) is supported in the literature. Yet most reports reflect institutional or personal bias. Aim: To evaluate the validity of ra...
Comparing the Results of Chest X-ray with Chest Ultrasound in Neonates Admitted in Neonatal Intensive Care Unit
ABSTRACT Introduction: Chest X-ray (CXR) is the potential method for the diagnosis of pulmonary disorders. It has been using in respiratory distress syndrome detection in neonates. Aim: To compare the diagnostic accuracy...
Evaluating a Risk Score for Lower Extremity Amputation in Patients with Diabetic Foot Infections
ABSTRACT Introduction: Factors associated with Diabetes Mellitus (DM) patients developing a foot ulcer are well defined, but risk factors for amputation are less clear. There are substantial morbidity and mortality asso...