Histopathological Changes in Kidney of Hatched Chicks on Exposure to Vapors of Different Concentration of Embalming Fluid during Incubation
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
The study is aimed at observation of any teratogenic /adverse effects upon histology of the chick kidney when exposed to two different embalming fluid vapors containing different concentrations of formalin during their incubation period (21 days). 100 fresh fertilized eggs of Gallus gallusdomesticus were taken and divided in to three groups. group I contained 20 eggs as control group, not exposed to any embalming fluid but allowed to incubate and hatch in normal conditions. Group II and group III having 40 eggs each were exposed to vapors of embalming fluid containing 106 mmol/lt of formalin and 53mmol/litre of formalin respectively. The hatchability rate of Group I, II and III was 60%, 42.5% and 52.5% respectively. On dissecting the kidney of all 3 groups, no gross pathological changes were observed but on histopathological examination following pathological changes were observed. Glomerular enlargement, glomerular congestion, mesangial proliferation and increased bowman’s space were maximum in group II followed by Group III. tubular changes like cystic dialatation and cloudy swelling in Proximal convoluted tubules were observed in group II and III but more prevalent in group II (17.64% and 41.17% respectively) . Diffused necrosis in group II was seen in 58.82% of cases while focal necrosis was observed in 38.09% cases in group III. Therefore it is concluded that embalming fluid containing more concentrations of formalin is nephrotoxic even in vapors form.
Authors and Affiliations
Drtanya Agarwal, Drviveksinha .
Keywords
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- EP ID EP251046
- DOI 10.9790/0853-1612081622
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