Histopathological evaluation of endoscopic biopsy specimens of ulcerative colitis
Journal Title: MedPulse -International Medical Journal - Year 2016, Vol 3, Issue 4
Abstract
Background: Nonneoplastic colorectal diseases including non specific colitis and ulcerative colitis are very common diseases all over the world and account for major portion of the gastrointestinal morbidity. Histopathological study of endoscopic colorectal biopsy plays a major role in the diagnosis of these diseases. Scoring of ulcerative colitis further establishes its role in the prognosis and helps clinicians in efficient patient management. Methodology: This is a prospective study of 33 patients who underwent endoscopic colorectal biopsies in various hospitals in and around Mangaluru and in Yenepoya Medical College and hospital, Mangaluru from October 2013 to September 2015. Histopathological diagnosis was made in each case in cases of ulcerative colitis scoring was done by K. Geboes scoring system. Results: Among the 33 cases studied of ulcerative colitis, twenty two (66.66%) were males (n=22) and eleven (33.33%) were females (n=11) with a ratio of 2:1. This indicates the male preponderance of ulcerative colitis. Ulcerative colitis cases were classified according to the Montreal classification. Maximum number of patients with ulcerative. colitis were in the age group of 56-65 years. Ulcerative colitis was more common among men compared to women (M: F=2:1). Ulcerative colitis cases were graded according to K. Geboes grading system. Most of the cases were in grade 4 and 5. Conclusion: Histopathological examination of endoscopic colorectal biopsies is a very useful tool in the accurate diagnosis of non-neoplastic colorectal diseases and excluding neoplastic diseases especially colorectal cancer.
Authors and Affiliations
Namrata Sharan Sinha, Krishnaraj Upadhyaya
Keywords
Related Articles
- EP ID EP205279
- DOI -
- Views 84
- Downloads 0
Gastric inflammatory myofibroblastic tumour in an adult – a rare manifestation
Inflammatory myofibroblastic tumor (IMFT) is usually a benign disease that is often mistaken for a malignant condition. We present a case of inflammatory pseudotumor from the greater curvature of the stomach of an adult...
Potential for misdiagnosis in a rare entity: A case report of kimura’s disease
Kimura disease (KD) is a rare form of chronic inflammatory disorder involving subcutaneous tissue, predominantly in the head and neck region and frequently associated with regional lymphadenopathy and/or salivary gland i...
Study of hematological profile of neonates born to mothers with hypertensive disorders of pregnancy as compared to normotensive mothers
Background: Pregnancies that are affected by hypertension have been accepted to have higher incidence of neonatal morbidity compared to those pregnancies with normal blood pressure, also these are complicated by an incre...
A study of the cases of fatal burn injuries in tertiary care hospital, Assam – autopsy based study
Death due to burn injury constitutes a major portion of the cases brought for autopsy to the Department of Forensic Medicine, Silchar Medical College, Silchar, Assam. A proper study of these cases is the need of the hour...
A study of outcome of posterior iris-claw lens at tertiary health care center
Background: The absence of adequate capsule support, complicates intraocular lens implantation at the time of penetrating keratoplasty. In such cases, an iris-supported anterior or posterior chamber intraocular lens, or...