Histopathological spectrum of lesions of upper gastrointestinal tract: A study of endoscopic biopsies
Journal Title: International Journal of Clinical and Diagnostic Pathology - Year 2018, Vol 1, Issue 2
Abstract
Background: Upper gastrointestinal tract disorders are one of the most commonly encountered problems in clinical practice. A variety of disorders can affect the upper GIT. The definitive diagnosis of upper gastrointestinal disorders rests on the histopathological confirmation and is one of the bases for planning proper treatment. Aims and objectives: To determine the spectrum of histopathological lesions of upper gastrointestinal tract and to establish endoscopic biopsies as an effective tool in the proper diagnosis and management of various upper gastrointestinal tract lesions. Materials and Methods: A prospective study was conducted on the upper GIT endoscopic biopsies and the histopathological assessment was done at the department of pathology, Subbaiah institute of medical sciences, Shimoga from July 2016 to July 2017. Results: A total of 144 cases were taken and 163 endoscopic biopsies were studied. There were 88 male patient and 56 female patients. An age range of 9‐88years was observed. There were 30 (18.4%) cases from esophagus, 05(3.06%) cases from GE junction, 93(57.05%) cases from stomach, 1 case (0.61) from neo stomach (GJstoma) and 34(20.85%) cases from duodenum. 100(61.34%) cases were non-neoplastic, 33(20.24%) cases were benign neoplasms while 30(18.40%) were malignant neoplasms. Histopathology revealed gastritis 63cases (63%) as the most frequently diagnosed inflammatory lesion while squamous cell carcinoma of esophagus, 19 cases (63.33%) comprised the most frequently diagnosed malignant lesion. Conclusion: In our study, the commonest site for upper GI endoscopic biopsy was from the stomach (57%) with 69.89% non neoplastic and 31.18% neoplastic lesions. Most common neoplasm of the stomach was adenocarcinoma. Endoscopy generates biopsy specimens from sites that were previously inaccessible without a major resection. So a thorough knowledge of the spectrum of lesions that can be diagnosed in these specimens is pertinent to make a proper diagnosis for better patient management.
Authors and Affiliations
Dr. Ganga H, Dr. Indudhara PB
Keywords
Related Articles
- EP ID EP541203
- DOI 10.33545/pathol.2018.v1.i2a.06
- Views 54
- Downloads 0
The utility of CK 19 & TPO expression in the diagnosis of thyroid nodules
Introduction: Thyroid lesion can be diagnosed using histopathological criteria which allows us to differentiate between benign and malignant lesion but in some cases suspicious areas were noted in few foci.in such cases...
Amino acids: Its types and uses
Amino acids are the organic compounds which contain amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) which is unique to each amino acid. In this paper, there is a description on how...
A study on multi site phase catalysts and their characterization
A suitable catalyst is required to execute the phase-transfer reaction. There are mainly three factors which are responsible for the phase-transfer reactions. First is that the catalyst should be capable of transferring...
Microscopic appearance of edible spices as intruders in histopathology
It is common for histopathologists to encounter food particles such as spices entrapped in various biopsy sections. Identification of these remains unresolved as they appear strange, leading to misdiagnosis. This study w...
Pleomorphic fibroma of skin: A case report
Pleomorphic fibroma of skin (PFS) is a benign, polypoid, or dome‑shaped cutaneous neoplasm with cytologically atypical fibrohistiocytic cells. We reported a case of PFS on the back of 55 years old male patient.