Histopathological study of meningioma
Journal Title: International Journal of Medical Science and Public Health - Year 2016, Vol 5, Issue 2
Abstract
Background: Meningioma, so named by Harvey Cushing in 1922, is a group of heterogeneous tumors that arise from meningothelial cells. Meningiomas are predominantly benign tumors usually attached to the dura mater that arise from the meningothelial cells of the arachnoids. Meningioma may be found along any of the external surface of the brain as well as within the ventricular system, where they arise from the stromal arachnoid cells of the choroid plexus. Objective: To evaluate the incidence of various histopathological variant of meningioma, its frequency in various parts of the brain, and its age and sex distribution. Materials and Methods: A total of 50 cases of meningioma (clinically diagnosed and histologically proved) admitted to neurosurgery units of a teaching hospital were studied. A detailed history was taken. Findings were recorded in the pro forma designated for the study. Result: Most common variant is meningothelial meningioma, 32 (64%) cases. According to the World Health Organization (WHO) grading, the most common WHO grade is grade 1 consisting of 45 (90%) cases and the most common site in central nervous system is intracranial. Female predominance is seen in meningioma. Conclusion: From our study, we can conclude that most common histopathological variants of meningioma are menin - gothelial meningioma followed by psammomatous meningioma, and least common is papillary meningioma. Most common WHO grade is grade 1. Benign meningiomas are most common meningioma. Intracranial location is the most common location for meningioma. Most common age group for presentation is middle-aged group of 31–50 years, and it is least common in children.
Authors and Affiliations
Pratik B Desai, Dhaval Patel
Keywords
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- EP ID EP112177
- DOI 10.5455/ijmsph.2016.04102015125
- Views 110
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