Histopathological study of non-neoplastic and neoplastic skin lesion by punch biopsy in west India - A three year study
Journal Title: Medpulse International Journal of Pathology - Year 2018, Vol 5, Issue 2
Abstract
Background: Dermatological disorders are common in all countries but the spectrum varies greatly with wide histological variation including both benign and malignant forms. Accurate diagnosis of skin disorders is of utmost importance as treatment is varied for different skin disorders presenting with the similar clinical lesions. Thus biopsy becomes inevitable in various skin disorders to confirm diagnosis and initiate treatment. Aims and Objectives: The present study is to analyse the age and sex distribution of dermatological disorders presenting to GMERS Medical College and Hospital, Gandhinagar and assess their histo-pathological profile. The objective is to analyse the histopathological profile of skin disorders presenting to the Dermatology department of the hospital, determine the age and sex distribution of various skin diseases and to classify the most common disorders into their subtypes and thus assess the most common subtypes prevalent in the surrounding community. Materials and Methods: In the period of 3 years, a hospital based retrospective study is carried out at the pathology department, GMERS Medical College and Hospital, Gandhinagar. Punch biopsy taken and sent to the histopathology section for final report. Formalin fixed, paraffin embedded sections were prepared and slides were routinely stained with H and E and special stains applied wherever necessary. Data obtained was tabulated and analysed. Results: In the period of January 2015 to December 2017, Total 324 skin biopsies were performed in histopathology department of GMERS Medical college, Gandhinagar. The Age distribution pattern revealed that the maximum biopsies received were in the age range of 21-30 years. Out of these patients, 186 cases males and 138 cases females. Conclusion: Skin lesions are more common in males than females. Granulomatous lesions were the most common skin disorders reported followed by Vesiculobullous lesion and Lichenoid lesions. Leprosy was the most common subtype of Granulomatous diseases.
Authors and Affiliations
Vaidehi Patel, Meeta Parikh, Nikunj Suthar
Keywords
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