Homeostatic Efficacy of Microporous Polysaccharide Hemosphere in Post-Operative Complications Reduction of Tubeless Percutaneous Nephrolithotomy
Journal Title: Translational Research in Urology - Year 2020, Vol 2, Issue 3
Abstract
Introduction Current hemostatic agents are needed to reduce bleeding and transfusion during several surgery processes. Plant-based absorbable surgical hemostatic agents (microporous polysaccharide hemospheres) are proposed for use in surgical wound sites as an absorbable hemostat and in this study, we checked its efficacy. Methods This study was run under the Tehran University of Medical Science Ethics Committee observation based on the clinical trial registry criteria (IRCT20190624043991N1). Total numbers of 42 percutaneous nephrolithotomies (PCNL) patients were enrolled, 21 cases hemostatic powder and 21 controls. Hemostatic powder pumped into Amplatz sheath before its extraction. Results The mean age of the case and control groups was 42.1±19.5, and 42.1±18.5 years, respectively. The median stone size was 11.3±1.85cm. Overall, the differences between sex, age, stone size, and location were not statistically significant in the two groups (p-value˃0.05). Serum hemoglobin reduction following PCNL was significant in both groups compared to the serum level before surgery (p-value<0.001). However, the difference was not significant between case and control groups postoperatively (p-value=0.727). Yet, postoperative serum creatinine reduction was not significantly different between the two groups compared to preoperative serum levels (p-value>0.05). Conclusions The present study showed that microporous polysaccharide hemosphere (MPH) did not affect bleeding reduction, hemoglobin decline, and postoperative blood transfusion, and hospital stay.
Authors and Affiliations
Seyed Mohammad Kazem Aghamir; Mahdi Ramezani-binabaj; Fatemeh Khatami; Behrooz Fatahi
Keywords
Related Articles
- EP ID EP704202
- DOI 10.22034/TRU.2020.257231.1047
- Views 91
- Downloads 0
Effect of Covid-2019 Infection on Main Sexual Function Domains in Iranian Patients
Introduction: The main purpose of this study was to investigate the relationship between Covid-2019 and sexual dysfunction. Methods: A cross-sectional study included the affected coronavirus disease 2019 patients in out...
An Unusual Extrarenal Renal Cell Carcinoma: Case Report
Introduction Renal cell carcinoma (RCC) is the most common type of kidney tumor. The extra-renal type has been previously reported only by few studies. In this type of RCC, cancerous tissue is present in regions other t...
Arsenic Trioxide; a Novel Therapeutic Agent for Prostate and Bladder Cancers
The effectiveness of arsenic trioxide (ATO) in treating blood diseases is one of the most striking developments in modern medicine. One of the most important benefits of ATO is the failure of bone marrow suppression. ATO...
The Alpha Blockers and the Ureteral Access Sheaths Placements
The new technique of laser applications with flexible ureteroscopy and retrograde intrarenal surgery (RIRS) applications has improved a lot over the last few years. Nowadays, it is possible to effectively accomplish RIRS...
The Molecular Structure and Case Fatality Rate of COVID-19
A new coronavirus recognized as 2019 novel coronavirus (COVID-19) is the etiological cause in charge of the 2019-2020 viral pneumonia worldwide outbreak. The molecular structure and genome of this virus are identical to...