Homology-Based Functional Relationships of Uncharacterized G8 Protein of Homo sapiens
Journal Title: Scholars Academic Journal of Biosciences - Year 2015, Vol 3, Issue 1
Abstract
Abstract: The G8 (for eight conserved glycine residues) domain is widely distributed, being found in Homo sapiens is analyzed by sequence similarity search using Blast and Clustal W. It reveals uncharacterized homologues, found in Pan troglodytes, Nomascus leucogenys , Pongo abelii and, Nomascus leucogenys. Data base searching results indicate that G8 protein of Homo sapiens is closely related to Pan troglodytes, Nomascus leucogenys , Pongo abelii and, Nomascus leucogenys. Phylogenetic analysis reveals that G8 protein of human shows maximum similarity with four uncharacterized protein of Pan troglodytes, Nomascus leucogenys , Pongo abelii and, Nomascus leucogenys. Discovery of G8 domain and its homologues will be important for the research of the structure/function of related proteins and beneficial for the development of novel therapeutics. Keywords: G8 domain, Data base searching, Blast, Clustal W, Protein sequence, Homology.
Authors and Affiliations
Padma Saxena
Keywords
Related Articles
- EP ID EP378288
- DOI -
- Views 73
- Downloads 0
Graves’ DiseaseHemodynamically Masquerading as Pheochromocytomaduring Thyroidectomy
Graves’ disease of thyroid occasionally requires surgical thyroidectomy for cure. In a well controlled (euthyroidised) patient with antithyroid drugs and beta blockers, it is a straight forward operation with uneventful...
A Prospective Study on Accidental Poisoning In Pediatric Patients
Toxicology is the science which deals with the chemical properties, action, toxicity, lethal dose, detection of various poisons and treatment of poisons. Poison is any substance which when introduced in to the living bod...
VACTERL Association: A Case Report in Newborn
VACTERL association is a useful acronym for a condition characterized by the sporadic, non-random association of specific birth defects of multiple organ systems. It includes vertebral anomalies (V), anal anomalies (A),...
Phenology of some medicinal plant species of Goalpara District, Assam (India)
: The study of various periodic behaviours of plant species or the phenology has great significance because it not only provides knowledge about the plant growth pattern but also provides the inferences on the effect of...
Response of Anisopteromalus calandrae (Hymenoptera: Pteromalidae) to variation in densities of its host Callosobruchus maculatus (Coleoptera: Chrysomelidae) within stored grains of Vigna subterranea (L.) Verdc (Fabaceae)
Bambara groundnut [Vigna subterranea (L.) Verdc (Fabaceae)] is an important source of protein for rural populations in sub-Saharan Africa. During storage, this commodity is destroyed by Callosobruchus maculatus (Coleopte...