HPV TYPES OF 2, 3, 4, AND 5 AMONG PATIENTS WITH LICHEN-PLANUS VERSUS CONTROL GROUP
Journal Title: Academic Research International - Year 2017, Vol 8, Issue 1
Abstract
Lichen planus is an idiopathic papulosquamous skin disease with purple itching papules mainly in extremities in leading to decreased quality of life and numerous problems in affected patients. Among the possible causes are viruses. Hence in this study the prevalence rate of HPV types of 2, 3, 4, and 5 was determined and compared among patients with lichen-planus and control group. In this case-control study, 28 consecutive patients with lichen-planus and 25 healthy subjects were enrolled. The prevalence rate of HPV types of 2, 3, 4, and 5 and existence of more than one type of HPV were determined by PCR method and compared across the groups. There were 50% and 84% HPV-2 positive samples in case and control groups, respectively showing significant difference (P=0.009). Also 42.9% in case and 8% HPV4 positive cases in case and control groups, respectively showing significant difference (P=0.004). Also the HPV types of 3 and 5 and existence of more than one HPV type were not significantly differed across the groups (P > 0.05). Totally it may be concluded that presence of some HPV types in lichen-planus patients is higher than control group ant lack of HPV type 2 and presence of type 4 may be risk factors for lichen-planus.
Authors and Affiliations
Nasrin Shayanfar
Keywords
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