Human Placentae in Pregnancy Induced Hypertension - A Histologic and Morphometric Analysis
Journal Title: International Journal of Anatomy and Applied Physiology (IJAAP) - Year 2018, Vol 4, Issue 3
Abstract
Introduction: Placenta is the mirror of maternal and fetal status. It has been called a pregnancy diary that permits the clinician to study the intra uterine environment of the fetus and some of the fetal responses to disease. Reduced maternal utero placental blood flow leading indirectly to constriction of foetal stem arteries has been associated with the changes seen in the placentae of pre-eclamptic women. Maternal vasospasm leads to fetal hypoxia, causing fetal distress and death. Histopathological changes related to confined placental mosaicism may be associated within adequate placentation and retroplacental ischemia. Aim: To study morphometry and histological changes in placentae of women with pregnancy induced hypertension (PIH) and to observe the perinatal outcome of such pregnancies. Materials: Total number of 50 placentae were used for the present study, out of which 25 placentae were obtained from women with PIH and 25 placentae from women who were normal having uncomplicated full-term deliveries. Results: The mean weight of the placenta was 470.04g in control group and 385.70g in PIH group. Histopathological examination of the placentain PIH showed increase in number of syncytial knots and areas of fibrinoid necrosis. Conclusion: PIH has remarkable influence on morphology and histology of the placenta, and there by affects the growth of fetus. The changes caused by placental insufficiency has an adverse affect on the neonatal birth weight due to compromised utero-placental blood flow.
Authors and Affiliations
Dhiren Punja
Keywords
Related Articles
- EP ID EP516420
- DOI 10.19070/2572-7451-1800017
- Views 99
- Downloads 0
Immature Coconut Water: A Renal Protective Agent in Wistar Rats
The biochemical characteristics of immature coconut water (ICW) have presented it as a therapeutic agent that can be used for preventive, management and curative purposes. Development of a more efficient and cost effecti...
Obligate Bipedal Locomotion in the Modern Human: A Review of Musculoskeletal Modifications
Several attributes are only found in primates, some of these are even more unique and noticeable in humans. These may not be limited to; energy-saving bipedal posture and locomotion, stable supine posture, complex manual...
Variations in Origin and Course of the Right and Left Coronary Arteries in Autopsied Hearts at the University Teaching Hospital, Lusaka, Zambia
Background: Coronary arteries play an important role in perfusion of the heart tissues. Variations or anomalies in coronary arteries may be asymptomatic while some can be symptomatic and even cause sudden death. Knowledg...
Accuracy of Fine Needle Aspiration of Pelvic Masses, A Cyto-histological Correlation
Objective: Evaluation of diagnostic efficacy of Fine Needle Aspiration Cytology in differential diagnosis of pelvic masses and correlation between histopathologic and FNA diagnoses. Methods: In this prospective study fif...
The Relation between Scapular Dyskinesis and the Upper Quarter Y-Balance Test
The shoulder is a complex mechanical system. Alterations in the position and/or orientation of its joints may interfere with optimal shoulder coordination. Scapular dyskinesis (SDK) is defined as mal-positioning or mal-m...