Hyperthermia and Rigidity Following Overdose of an Unknown Drug; A Case Report and Literature Review
Journal Title: Bulletin of Emergency And Trauma - Year 2018, Vol 6, Issue 3
Abstract
Drug induced hyperthermia is a rare presentation which can rapidly lead to gross metabolic abnormality and death. These presentations are further complicated by the wide range of potentially causative agents. We present a case of rigidity and hyperthermia, following overdose of an initially unknown substance leading to challenging management decisions in the Emergency Department. This case was later identified as Serotonin Syndrome. The patient presented with trismus which was managed with rapid sequence induction of anaesthesia to allow airway protection. On extubation a significant degree of laryngeal oedema complicated weaning, a possible complication of Serotonin Syndrome not previously described in the literature. We discuss the pathophysiology of Serotonin Syndrome, important differentials and practical considerations in managing hypertonicity of unknown origin in a young person.
Authors and Affiliations
Rose Dean-Paccagnella, Matthew Creed, Mahendra Kakollu, Suresh Kumar Gopala Pillai
Keywords
Related Articles
- EP ID EP333853
- DOI 10.29252/beat-060311
- Views 90
- Downloads 0
Isolated Traumatic Brachialis Muscle Tear: A Case Report and Review of Literature
Isolated traumatic brachialis muscle tears are uncommonly reported – leading to occasional misdiagnosis and misdirected treatment. The rarity of brachialis muscle tear may promote misdiagnosis or mistreatment of this inj...
The Predictive Value of Repeated Abdominal Ultrasonography in Patients with Multiple Trauma and Decreased Level of Consciousness: The Experience of a Resource-Limited Centre
Objective: To determine the predictive value of repeated abdominal ultrasonography in patients with multiple trauma and decreased level of consciousness (LOC). Methods: This prospective cross-sectional study was conducte...
Effects of Unilateral Iatrogenic Vas Deferens Trauma on Fertility: An Experimental In Vitro Fertilization Mice Model Study
Objective: To determine bilateral effects of unilateral iatrogenic vas deferens trauma (UIT) on epididymal sperm characteristics and in vitro fertilizing capacity in an experimental mouse model. Methods: Experiments were...
Femoral Shaft Fracture during Bungee Jump: A Case Report and Literature Review
Bungee jumping is a recreational sport that is accepted to carry a level of risk. We present the case of a femoral fracture sustained during bungee jumping and examine the published literature on bungee jumping-related i...
Closing a Tracheal Defect with an Omental Pedicled Gastric Flap; A Technical Note
Due to an adenocarcinoma of the right upper lobe with infiltration of the main bronchus a 49-years-old female patient underwent an upper bilobectomy with sleeve resection. After two completed chemotherapy bouts and signs...