Hypoalbuminemia and Related Factors in Hemodialyzed Patients: A Study of Six Centers in Turkey
Journal Title: The Medical Bulletin of Haseki - Year 2019, Vol 57, Issue 4
Abstract
Aim: It is known that low serum albumin levels are related to mortality in hemodialysis (HD) patients. In this study, it was aimed to determine factors which may affect serum albumin level and investigate any gender variation in serum albumin concentration. Methods: The data of this study was obtained by the analysis of the records of 306 patients. The patients were divided into two groups; albumin <3.8 g/dL and ≥3.8 g/dL. Albumin was determined as a dependent variable of the study, while age, sex, dialysis adequacy parameters, C-reactive protein (CRP), anemia status and presence of diabetes mellitus were determined as independent variables. As statistical examination, chi-square test and logistic regression were used. A p value of <0.05 was considered statistically significant (Confidence interval=95%). Results: The Odds ratio for hypoalbuminemia was 3.1 times higher for women compared to men (CI: 1.6-6.0, p=0.001), 5.5 times higher for patients with Kt/V<1.4 (CI: 2.5-11.9, p=0.001), 2.9 times higher for patients with CRP>1.0 mg/dL (CI: 1.5-5.6, p=0.001) and was 4.9 times higher for patients with hemoglobin (Hb) <11 g/dL (CI: 2.6-9.2, p=0.001). Conclusion: These results indicate that when hypoalbuminemia is detected in HD patients, gender, adequacy of dialysis, Hb levels and causes of inflammation should be considered.
Authors and Affiliations
Halil İbrahim Erdoğdu, Eray Atalay
Keywords
Related Articles
- EP ID EP675947
- DOI 10.4274/haseki.galenos.2019.5444
- Views 203
- Downloads 0
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