HYPOGLYCEMIC ACTIVITY OF PASSIFLORA EDULIS SIMS LEAF EXTRACT IN WISTAR ALBINO RATS
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 9
Abstract
The traditional medicinal plant P.edulis was tested for its hypoglycemic effect in Wistar albino rats. The oral glucose tolerance test was performed in overnight fasted normal as well as in alloxan induced diabetic rats (150 mg/kg, of alloxan, i.p.) with the administration of 100,200,300,400 mg/kg of b.wt of P.edulis. The blood sample withdrawn at 0, 60, 120, 180 min of glucose administration from the retro orbital sinus by capillary puncture indicated the hypoglycemic nature of the P.edulis leaf extract and identified the most effective dose as 200mg/kg b.wt.
Authors and Affiliations
Devaki Kanakasabapathi , Beulah Uthamaraj , Akila Govindraj , Sunitha Martin , Kanniappan Velliyur
Keywords
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- EP ID EP103290
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