Hyponatremia in Children with Acute Lower Respiratory Tract Infections: An Institutional Based Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 5
Abstract
Background: Lower respiratory tract infection (LRTI) is among the serious health problems specifically in less than 5 years of age needing hospitalisation and attributes to 30 % of deaths yearly worldwide especially due to pneumonia as the leading cause. In developing country like India patients with pneumonia and bronchiolitis, the most typical diseases come across in pediatric basic practice, are at particular danger of establishing hyponatremia due to antidiuretic hormonal agent (ADH) over secretion or it might also arise from a salt deficit, or surplus of water, which can contribute the child motility rate. Objective: The objective of this study is to compare the sodium and CRP level in children with LRTI, and to highlight the more important aspect in this subject. Materials and Methods: Total of 100 children between the age group of 2 months to 5 years where taken in this study. Out of which 50 children were control and 50 were known cases of lower respiratory tract infection mainly pneumonia. Aseptically, 3 ml of venous blood was drawn from the antecubital vein from each patient and were analysed for serum sodium level and serum CRP level. Statistical analysis of collected data has been done by using SPSS (16.0). P value < 0.05 was considered as statistically significant. Results: Statistically significant differences were observed in the mean serum sodium level of controls and CRP as compared to children with pneumonia (138±2.63 mmol/L), (129 ± 3.215 mmol/L) (p = 0.004) and (6.11 ± 2.79 mg/L). (p= 0.02) respectively. While, after applying Pearson’s correlation coefficient it was found that there is a negative correlation between serum sodium level and CRP (r = -0.290) in cases. Whereas, in control it do not shows any significant relations. Conclusion: Hyponatremia has clearly been shown to be a common electrolyte abnormality in lower respiratory tract disease mainly in pneumonia. Thus, serum electrolytes should be measured in children hospitalised for pneumonia; the appropriate fluid therapy must be carefully arranged in children with hyponatraemia for appropriate management resulting in better outcome of the patient.
Authors and Affiliations
Sachin Walchand Shah, Sudhir Shantilal Mavadia, Pankaj Kupvade
Keywords
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- EP ID EP536592
- DOI 10.21276/ijmrp.2018.4.5.003
- Views 75
- Downloads 0
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