Hyponatremia in Children with Acute Lower Respiratory Tract Infections: An Institutional Based Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 5
Abstract
Background: Lower respiratory tract infection (LRTI) is among the serious health problems specifically in less than 5 years of age needing hospitalisation and attributes to 30 % of deaths yearly worldwide especially due to pneumonia as the leading cause. In developing country like India patients with pneumonia and bronchiolitis, the most typical diseases come across in pediatric basic practice, are at particular danger of establishing hyponatremia due to antidiuretic hormonal agent (ADH) over secretion or it might also arise from a salt deficit, or surplus of water, which can contribute the child motility rate. Objective: The objective of this study is to compare the sodium and CRP level in children with LRTI, and to highlight the more important aspect in this subject. Materials and Methods: Total of 100 children between the age group of 2 months to 5 years where taken in this study. Out of which 50 children were control and 50 were known cases of lower respiratory tract infection mainly pneumonia. Aseptically, 3 ml of venous blood was drawn from the antecubital vein from each patient and were analysed for serum sodium level and serum CRP level. Statistical analysis of collected data has been done by using SPSS (16.0). P value < 0.05 was considered as statistically significant. Results: Statistically significant differences were observed in the mean serum sodium level of controls and CRP as compared to children with pneumonia (138±2.63 mmol/L), (129 ± 3.215 mmol/L) (p = 0.004) and (6.11 ± 2.79 mg/L). (p= 0.02) respectively. While, after applying Pearson’s correlation coefficient it was found that there is a negative correlation between serum sodium level and CRP (r = -0.290) in cases. Whereas, in control it do not shows any significant relations. Conclusion: Hyponatremia has clearly been shown to be a common electrolyte abnormality in lower respiratory tract disease mainly in pneumonia. Thus, serum electrolytes should be measured in children hospitalised for pneumonia; the appropriate fluid therapy must be carefully arranged in children with hyponatraemia for appropriate management resulting in better outcome of the patient.
Authors and Affiliations
Sachin Walchand Shah, Sudhir Shantilal Mavadia, Pankaj Kupvade
Keywords
Related Articles
- EP ID EP536592
- DOI 10.21276/ijmrp.2018.4.5.003
- Views 86
- Downloads 0
Knowledge About Asthma Among Primary School Teachers in Riyadh City, Saudi Arabia
Background: Adequate asthma knowledge among school teachers is critical for the safety of their students who are suffering asthma exacerbation during the school time. Objective: To assess asthma knowledge and it’s associ...
The Diagnosis of Lumbar Disc Degenerative Disease and Role of MRI: A Hospital Based Study
Background: Degenerative Lumbar Disc (DLD) is widespread cause for lower back ache (LBA) Early diagnosis is most important in the treatment of DLD. Our study aimed to find out the role of MRI in the detection of degenera...
Long Term Consumption of High Dose Sucralose Induces Hepatic Necrosis and Fibrosis in Male Albino Rats
Background: Sucralose is one of the most popular non-nutritive sweeteners in the market. Whoever its toxicological effect are still need further investigation Materials and Methods: Three groups of 50 rats formed of a co...
Evaluation of Efficacy of Three-Port V/s Standard Four-Port Laparoscopic Cholecystectomy in Patients of Symptomatic Cholelithiasis: An Institutional Based Study
Background: Laparoscopic cholecystectomy is a minimally invasive surgical procedure for removal of a diseased gallbladder. Traditional LC is performed using four-port technique. Reducing the size or number of ports did n...
Role of ARFI Elastography in Assessment of Differences in Quantitative Placental Elasticity in Normal Versus Intra Uterine Growth Retarded Pregnancies
Objective: This study is aimed at comparing quantitative elasticity of placenta using acoustic radiation force impulse (ARFI) elastography in normal versus intra uterine growth retarded pregnancies. Materials and Methods...