Hysteroscopic Embryo Transfer or Implantation- Experience of a Decade: An Alternative Objective and Reliable Method for Embryo Transfer (HEED) and Implantation (SEED)
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2015, Vol 6, Issue 7
Abstract
Aims: Here we present early experience using HEED and SEED along with a description of these procedures in more detail. There is also a new look at the endometrial cavity and the placement of embryo transfer or implantation while under direct visualization. Study Design: Retrospective non-randomized and uncontrolled case series. Place and Duration of Study: West Coast IVF Clinic, Inc. and LA IVF Lab, LLC, Beverly Hills, CA, USA, between June, 2002 and June, 2011. Methodology: Embryo transfer was done using a mini flexible hysteroscope with an articulating tip. This was accomplished by either placing the embryo gently on the surface of the endometrium (HEED) in 35 patients undergoing IVF, or embedding the embryo just beneath the endometrial surface (SEED) in 24 patient starts using egg donation. Once pregnancy was confirmed with a positive serum hCG, they were followed up with transvaginal ultrasounds and serial serum hCG’s in the first trimester. They were then referred to their local obstetricians and final outcomes were recorded after deliveries. Results: There were a total of 35 patients in the early (days 2 or 3) embryo transfer group (HEED) which resulted in 16(46%) total pregnancies, which included 2 biochemical pregnancies, 2 ectopics, 5 spontaneous miscarriages, and 3 multiple pregnancies. There were 7 (20%) live births. In the second group of patients with day 5 or 6 embryo implantations (SEED), there were a total of 24 patient starts, with 16(67%), 4, 0, 5, and 4 total, biochemical, ectopic and multiple pregnancies respectively. There were 7(29%) live births. Conclusion: Hysteroscopic embryo transfer or implantation may increase successful pregnancies and decrease risks and side effects from IVF procedures. Further prospective, controlled and randomized studies are needed to determine effectiveness of these procedures.
Authors and Affiliations
Michael Kamrava, Mei Yin
Keywords
Related Articles
- EP ID EP347245
- DOI 10.9734/BJMMR/2015/15395
- Views 55
- Downloads 0
Prevalence of AmpC Beta-lactamase in Gram Negative Bacilli by Different Phenotypic Methods in a Tertiary Care Institute in Kashmir
Context: AmpC type cephalosporinases are Ambler class C β-lactamases. They hydrolyze penicillins, cephalosporins; except the fourth-generation compounds and monobactams. To the best of our knowledge prevalence of AmpC in...
Estimated Glomerular Filtration Rate in Patients with Lower Urinary Tract Symptoms/Benign Prostatic Obstruction in an Emerging Tertiary Centre
Background: The association of benign prostatic hypertrophy (BPH) and chronic kidney disease (CKD) has been a subject of controversies. Combinations of recurrent urinary tract infections, chronic retention with large res...
Assessment of Post Dural Puncture Headache in Patients Undergoing Caesarean Section: A Comparison between 25 G Quinke V/S Whitacre Needles
Background: PDPH (post dural puncture headache) is a common complication of subarachnoid block and results from iatrogenic puncture of the duramater. Size of the dural puncture [1,2], age of the patient, needle tip desi...
Differences and Relationships between Morphometric Parameters and Zinc Content in Nonhyperplastic and Hyperplastic Prostate Glands
Aims: To clarify the changes in morphometric parameters and contents of zinc (Zn) and in the relationship between these characteristics in normal and hyperplastic human prostates, a quantitative morphometry and energy-di...
Neutrophil to Lymphocyte Ratio in Sickle Cell Anaemia Patients with Nephropathy
Background: Sickle cell anaemia (SCA) is associated with a chronic inflammatory component; blood neutrophil to lymphocyte ratio (NLR) has been described as a marker of organ dysfunction and clinical outcome in diseases a...