Identification of Molecular sequence relationships between Culex quinquefasciatus and Aedes aegypti using Bioinformatics techniques
Journal Title: International Journal of Novel Trends in Pharmaceutical Sciences - Year 2015, Vol 5, Issue 3
Abstract
When two symbolic representations of DNA or protein sequences are arranged next to one another so that their most similar elements are juxtaposed they are said to be aligned. Many bioinformatics tasks depend upon successful alignments. Alignments are conventionally shown as traces. In this research work we try to find out the molecular sequence similarity of Culex quinquefasciatus - multidrug resistance protein using bioinformatics techniques. The results obtained from our current researh explain how the Culex quinquefasciatus - multi drug resistance protein is molecularly related to Aedes aegypti species. We also represent the molecular functional part of the target protein sequences in culex and aedes species. In future, the same chemical compounds can be used to inhibit the protein targets of the two species using Cheminformatics studies.
Authors and Affiliations
A. Joshua Andrews , Muthupandi M , Ronald Nathanael S , Junas Ekka , Madavan S. P , John Williams. S
Keywords
Related Articles
- EP ID EP123442
- DOI -
- Views 122
- Downloads 0
Marine Organism: Lead Compounds and as a Source of New Antiviral Agents
Natural product lead compounds from various marine sources have often been found to be promising pharmaceutical agents. Several of them have successfully been approved as antiviral agents for clinical use or have been ad...
Lyophilization/Freeze Drying - An Review
On 21st century, in pharmaceutical field lyophilization has become important subject to ongoing development and its expansion. Lyophilization is common, but cost intensive. In old days process optimization was focused on...
Protein –protein docking studies on diabetes mellitus using insilico methods
Concurrent with the spread of the western lifestyle, the prevalence of all types of diabetes is on the rise in the world's population. The number of diabetics is increasing by 4-5% per year. It was long believed that the...
Structural Analysis and Molecular Mechanics of Pxr1 Gene which is Responsible For Zellweger Syndrome
Zellweger syndrome is an autosomal recessive disorder caused by mutations in genes that encode peroxins, proteins required for the normal assembly of peroxisomes. It causes a defect is the perioxisomes, which affects the...
Protein modelling, identification of de novo chemical inhibitor and QSAR studies on PCOS (Polycystic Ovary Syndrome) using cheminformatics software and tools
In this Insilico research project, Polycystic Ovary syndrome analysis was carried out. Protein modeling and drug designing were major steps for delivering the best drug candidates for disease target. The identified prote...