IDENTIFICATION OF NEW MOLECULAR BIOMARKERS - PROTEOMICS
Journal Title: SANAMED - Year 2018, Vol 13, Issue 1
Abstract
The pathogenesis of the tumor is extremely complex and can not be fully explained by the existing methodological approaches. Proteomics is an interdisciplinary science that deals with the study of proteins, carriers of the biological functions of the organism. It encompasses a series of methods for protein analysis and provides exceptional possibilities for understanding the molecular basis of the disease, the possibilities of early diagnosis, and the production of new drugs. Proteomic analyzes of the malignancy altered tissue have revealed proteins involved in the progression of the disease, and thus contributed to the discovery of potential drug treatment methods. Proteomics provides a better understanding of the molecular basis of these diseases, plays a role in the diagnosis of the same, and it is expected to make a significant contribution to the development of new more effective drugs and the development of personalized therapy
Authors and Affiliations
Sladjana Vujacic
PURE RED CELL APLASIA INDUCED BY ERYTHROPOIETIN
Introduction: Recombined human erythropoietin has been present in clinical practice for more than 20 years, in these therapeutic indications: anemia in kidney insufficiency, anemia during chemotherapy of tumors, preventi...
PLACING A THREADED PLUG IN THE HOLE OF A LOCKING PLATE AT THE FRACTURE LEVEL CAN INCREASE THE RESISTANCE OF THE PLATE:A BIOMECHANICAL STUDY
Objectives: This study aimed to evaluate whether placing a threaded plug in the hole of a locking plate at the fracture level is beneficial for increasing the resistance of the plate. Methods: This experimental study an...
THE ROLE OF CANDIDA ALBICANS ON THE DEVELOPMENT OF STOMATITIS IN PATIENTS WEARING DENTURES
Denture stomatitis is the most common inflammatory reaction that occurs in people who wear dentures. It is believed that in 60-65% of cases the cause of this inflammation is infections by yeasts from the genus Candida (C...
VAGINAL HYSTERECTOMY COMPARED TO ABDOMINAL AND LAPAROSCOPIC HYSTERECTOMIES IN PATIENTS WITHOUT UTERINE PROLAPSE
Introduction: Except for the uterine prolapse indication, vaginal hysterectomy has been less popular than abdominal hysterectomy because the latter is considered safer and easier and surgeons often lack sufficient experi...
EFFECT OF SUGAMMADEX AND NEOSTIGMINE ON BLOOD GLUCOSE LEVEL:A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL
Objectives: Sugammadex is offered as a recent alternative to cholinesterase inhibitors in reversing neuromuscular block. Sugammadex is a cyclodextrin molecule that is consisted of bounded sugar molecules. Given its chemi...