Imaging of ovarian cancer: Current concepts.
Journal Title: Hellenic Journal of Radiology - Year 2018, Vol 3, Issue 4
Abstract
Despite the advances in medicine over the past decades, ovarian cancer remains a major clinical and radiological challenge worldwide, with the highest mortality rate among gynaecologic malignancies. Modern histopathological and molecular genetic studies contributed to understand the pathogenesis of ovarian cancer, which now includes a heterogeneous group of malignant epithelial tumours that share the same origin as tubal cancer and peritoneal primary cancer. Based on this knowledge, the International Federation of Gynaecology and Obstetrics (FIGO) staging system was revised in 2014, providing better prognostic information and reinforcing personalised management of ovarian cancer. In accordance, there are now evidence-based imaging recommendations that provide accurate characterisation of adnexal masses that all radiologists should be aware of. Accurate mapping of tumour burden and distribution of disease by imaging plays a central role in treatment stratification and in predicting the success of cytoreductive surgery. The purpose of this article is to review the clinicopathological characteristics of ovarian cancer and their impact on radiological assessment, staging and therapeutic approach.
Authors and Affiliations
Rui Tiago Gil, Teresa Margarida Cunha, Mariana Horta
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